dc.contributor.author | Cuthbertson, Brian | en |
dc.contributor.author | Amiri, Amir R. | |
dc.contributor.author | Croal, Bernard L. | |
dc.contributor.author | Rajagopalan, Sriram | |
dc.contributor.author | Brittenden, Julie | |
dc.contributor.author | Hillis, Graham S. | |
dc.date.accessioned | 2007-11-16T12:52:16Z | |
dc.date.available | 2007-11-16T12:52:16Z | |
dc.date.issued | 2007 | |
dc.identifier.citation | Cuthbertson, B.H., Amiri, A.R., Croal, B.L., Rajagopalan, S., Brittennden, J., and Hillis, G.S. (2007). Utility of B-type natriuretic peptide in predicting medium-term mortality in patients undergoing major non-cardiac surgery. American Journal of Cardiology, 100(8), pp.1310-1313. | en |
dc.identifier.issn | 0002-9149 | |
dc.identifier.other | PURE: 427399 | en |
dc.identifier.uri | http://hdl.handle.net/2164/171 | |
dc.description.abstract | We assessed the ability of pre-operative B-type natriuretic peptide (BNP) levels to predict medium-term mortality in patients undergoing major noncardiac surgery. During a median 654 days follow-up 33 patients from a total cohort of 204 patients (16%) died. The optimal cut-off in this cohort, determined using a receiver operating characteristic curve, was >35pg.mL-1. This was associated with a 3.47-fold increase in the hazard of death (p=0.001) and had a sensitivity of 70% and a specificity of 68% for this outcome. These findings extend recent work demonstrating that BNP levels obtained before major noncardiac surgery can be used to predict peri-operative morbidity, and indicate that they also forecast medium-term mortality. | en |
dc.description.sponsorship | This work was supported by a grant from TENOVUS Scotland. The Health Services Research Unit is core-funded by the Chief Scientists Office of the Scottish Executive Health Department. | en |
dc.format.extent | 216725 bytes | |
dc.format.extent | 3 p. | en |
dc.format.mimetype | application/pdf | |
dc.language.iso | en | en |
dc.publisher | Elsevier | en |
dc.subject | Biological Markers | en |
dc.subject | Mortality | en |
dc.subject | Postoperative Complications | en |
dc.subject | Surgery | en |
dc.subject.lcc | RD Surgery | en |
dc.title | Utility of B-type natriuretic peptide in predicting medium-term mortality in patients undergoing major non-cardiac surgery | en |
dc.type | Journal Article | en |
dc.type | Text | en |
dc.contributor.institution | University of Aberdeen, School of Medicine & Dentistry, Division of Applied Health Sciences | en |
dc.contributor.institution | University of Aberdeen, School of Medicine & Dentistry, Division of Applied Medicine | en |
dc.description.status | Peer reviewed | en |
dc.description.version | Author version | en |
dc.identifier.doi | http://dx.doi.org/10.1016/j.amjcard.2007.05.058 | |