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Associations of autozygosity with a broad range of human phenotypes

dc.contributor.authorMurray, Alison D.
dc.contributor.authorClark, David W.
dc.contributor.authorYukinori, Okada
dc.contributor.authorKristjan H S, Moore
dc.contributor.authorMason, Dan
dc.contributor.authorPirastu, Nicola N
dc.contributor.authorconsortium, ROHgen
dc.date.accessioned2019-11-04T14:25:01Z
dc.date.available2019-11-04T14:25:01Z
dc.date.issued2019-10-31
dc.identifier147477425
dc.identifier033f40af-3f3a-41fa-abfb-0f1eba759b4f
dc.identifier85074297784
dc.identifier000493438700005
dc.identifier31673082
dc.identifier.citationMurray , A D , Clark , D W , Yukinori , O , Kristjan H S , M , Mason , D , Pirastu , N N & consortium , ROH 2019 , ' Associations of autozygosity with a broad range of human phenotypes ' , Nature Communications , vol. 10 , 4957 . https://doi.org/10.1038/s41467-019-12283-6en
dc.identifier.issn2041-1723
dc.identifier.otherORCID: /0000-0003-4915-4847/work/76976604
dc.identifier.urihttps://hdl.handle.net/2164/13221
dc.descriptionThis paper is the work of the ROHgen consortium. We thank the Sigma T2D Consortium, whose members are detailed in Supplementary Note 3. We thank the UK Biobank Resource, approved under application 19655; we acknowledge funding from the UK Medical Research Council Human Genetics Unit and MRC Doctoral Training Programme in Precision Medicine. We also thank Neil Robertson, Wellcome Trust Centre for Human Genetics, Oxford, for use of his author details management software, Authorial. Finally, we thank all the participants, researchers and funders of ROHgen cohorts. Cohort-specific acknowledgements are in Supplementary Data 2; personal acknowledgements and disclosures are in Supplementary Note 2. We thank Rachel Edwards for administrative assistance.en
dc.format.extent5244767
dc.language.isoeng
dc.relation.ispartofNature Communicationsen
dc.subjectBreeding Successen
dc.subjectReproductionen
dc.subjectgenetic varianceen
dc.subjectHomozygosityen
dc.subjectSocial Factorsen
dc.subjectPhenotypesen
dc.subjectFertilityen
dc.subjectInbreedingen
dc.subjectInbreeding depressionen
dc.subjectProgenyen
dc.subjectOffspringen
dc.subjectChildrenen
dc.subjectQUANTIFICATIONen
dc.subjectLOCIen
dc.subjectRUNSen
dc.subjectFERTILITYen
dc.subjectHOMOZYGOSITYen
dc.subjectINBREEDING DEPRESSIONen
dc.subjectR Medicine (General)en
dc.subjectGeneral Physics and Astronomyen
dc.subjectGeneral Chemistryen
dc.subjectGeneral Biochemistry,Genetics and Molecular Biologyen
dc.subjectMedical Research Council (MRC)en
dc.subjectWellcome Trusten
dc.subject.lccR1en
dc.titleAssociations of autozygosity with a broad range of human phenotypesen
dc.typeJournal articleen
dc.contributor.institutionUniversity of Aberdeen.Grampian Data Safe Haven (DaSH)en
dc.contributor.institutionUniversity of Aberdeen.Institute of Medical Sciencesen
dc.contributor.institutionUniversity of Aberdeen.Applied Medicineen
dc.contributor.institutionUniversity of Aberdeen.Aberdeen Biomedical Imaging Centreen
dc.description.statusPeer revieweden
dc.identifier.doi10.1038/s41467-019-12283-6
dc.identifier.urlhttp://www.scopus.com/inward/record.url?scp=85074297784&partnerID=8YFLogxKen


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