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dc.contributor.authorKarystinou, Alexandra
dc.contributor.authorRoelofs, Anke Jozefien
dc.contributor.authorNeve, Anna
dc.contributor.authorCantatore, Francesco P
dc.contributor.authorWackerhage, Henning
dc.contributor.authorDe Bari, Cosimo
dc.date.accessioned2016-08-25T16:00:03Z
dc.date.available2016-08-25T16:00:03Z
dc.date.issued2015-05-30
dc.identifier50237800
dc.identifier01dbd9ef-0a49-4746-bcec-c11f079590f1
dc.identifier84930211132
dc.identifier.citationKarystinou , A , Roelofs , A J , Neve , A , Cantatore , F P , Wackerhage , H & De Bari , C 2015 , ' Yes-associated protein (YAP) is a negative regulator of chondrogenesis in mesenchymal stem cells ' , Arthritis Research & Therapy , vol. 17 , 147 . https://doi.org/10.1186/s13075-015-0639-9en
dc.identifier.issn1478-6354
dc.identifier.urihttp://hdl.handle.net/2164/7388
dc.descriptionThis is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. Acknowledgements The authors would like to thank Dr Marius Sudol for the hYAP plasmids (obtained through Addgene), Dr Pete Zammit for the pMSCV-IRES-eGFP plasmid, Dr Robert Judson for subcloning the hYAP cDNAs into the pMSCV-IRES-eGFP plasmid, Dr Lynda Erskine for the provision of mouse embryo samples, and Professor Jimmy Hutchison and the Orthopaedics Department at the Aberdeen Royal Infirmary for the provision of human tissue samples. The authors are also grateful to Denise Tosh and Susan Clark for excellent technical support. This work was funded by Arthritis Research UK (grant 19429).en
dc.format.extent14
dc.format.extent2395270
dc.language.isoeng
dc.relation.ispartofArthritis Research & Therapyen
dc.subjectmesenchymal stem cellsen
dc.subjectYAPen
dc.subjectTAZen
dc.subjectchondrogenesisen
dc.subjecttransforming growth factor betaen
dc.subjectbone morphogenetic proteinsen
dc.subjectSmad signallingen
dc.subjectcartilage repairen
dc.subjectosteparthritisen
dc.subjectR Medicineen
dc.subjectSupplementary Dataen
dc.subject.lccRen
dc.titleYes-associated protein (YAP) is a negative regulator of chondrogenesis in mesenchymal stem cellsen
dc.typeJournal articleen
dc.contributor.institutionUniversity of Aberdeen.Applied Medicineen
dc.contributor.institutionUniversity of Aberdeen.Aberdeen Centre for Arthritis and Musculoskeletal Health (ACAMH)en
dc.contributor.institutionUniversity of Aberdeen.Medical Sciencesen
dc.description.statusPeer revieweden
dc.identifier.doi10.1186/s13075-015-0639-9


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