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Histopathological Defects in Intestine in Severe Spinal Muscular Atrophy Mice Are Improved by Systemic Antisense Oligonucleotide Treatment

dc.contributor.authorSintusek, Palittiya
dc.contributor.authorCatapano, Francesco
dc.contributor.authorAngkathunkayul, Napat
dc.contributor.authorMarrosu, Elena
dc.contributor.authorParson, Simon H.
dc.contributor.authorMorgan, Jennifer E.
dc.contributor.authorMuntoni, Francesco
dc.contributor.authorZhou, Haiyan
dc.date.accessioned2016-05-13T11:00:12Z
dc.date.available2016-05-13T11:00:12Z
dc.date.issued2016-05-10
dc.identifier66129627
dc.identifierf4c1bfbe-5e54-496b-b741-7d565c198a52
dc.identifier27163330
dc.identifier27163330
dc.identifier84968867089
dc.identifier.citationSintusek , P , Catapano , F , Angkathunkayul , N , Marrosu , E , Parson , S H , Morgan , J E , Muntoni , F & Zhou , H 2016 , ' Histopathological Defects in Intestine in Severe Spinal Muscular Atrophy Mice Are Improved by Systemic Antisense Oligonucleotide Treatment ' , PloS ONE , vol. 11 , no. 5 , 0155032 , pp. 1-15 . https://doi.org/10.1371/journal.pone.0155032en
dc.identifier.issn1932-6203
dc.identifier.otherORCID: /0000-0002-8848-8738/work/82379602
dc.identifier.urihttp://hdl.handle.net/2164/5986
dc.descriptionAcknowledgments This study is supported by the National Institute for Health Research Biomedical Research Centre at Great Ormond Street Hospital for Children NHS Foundation Trust and University College London (FM and HZ), the Medical Research Council grant (grant reference MR/L013142/1, FM), SMA-Europe grant (FM and HZ) and Great Ormond Street Hospital Children’s Charity grants (FM and HZ). JEM is supported by Great Ormond Street Hospital Children’s Charity. PS is supported by Bill Marshall Fellowship and The CP Charitable Trust at Great Ormond Street Hospital and UCL. SHP is supported by SMA Trust and Euan MacDonald Centre for Motor Neurone Disease Research.en
dc.format.extent15
dc.format.extent6123314
dc.language.isoeng
dc.relation.ispartofPloS ONEen
dc.subjectR Medicineen
dc.subjectMedical Research Council (MRC)en
dc.subjectMR/L013142/1en
dc.subjectNational Institute for Health Research (NIHR)en
dc.subject.lccRen
dc.titleHistopathological Defects in Intestine in Severe Spinal Muscular Atrophy Mice Are Improved by Systemic Antisense Oligonucleotide Treatmenten
dc.typeJournal articleen
dc.contributor.institutionUniversity of Aberdeen.Medical Educationen
dc.contributor.institutionUniversity of Aberdeen.Institute of Medical Sciencesen
dc.contributor.institutionUniversity of Aberdeen.The Suttie Centre - Anatomyen
dc.description.statusPeer revieweden
dc.identifier.doi10.1371/journal.pone.0155032


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