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Plasma non-esterified docosahexaenoic acid is the major pool supplying the brain : Plasma NEFA pool supplies the brain with DHA

dc.contributor.authorChen, Chuck T.
dc.contributor.authorKitson, Alex P.
dc.contributor.authorHopperton, Kathryn E.
dc.contributor.authorDomenichiello, Antony F
dc.contributor.authorTrepanier, Mark O.
dc.contributor.authorLin, Lauren E.
dc.contributor.authorErmini, Leonardo
dc.contributor.authorPost, Martin
dc.contributor.authorThies, Frank
dc.contributor.authorBazinet, Richard P.
dc.date.accessioned2016-01-29T14:25:02Z
dc.date.available2016-01-29T14:25:02Z
dc.date.issued2015-10-29
dc.identifier57242875
dc.identifiera85991a0-e9af-4d90-a6c7-deea250e98be
dc.identifier84946140531
dc.identifier.citationChen , C T , Kitson , A P , Hopperton , K E , Domenichiello , A F , Trepanier , M O , Lin , L E , Ermini , L , Post , M , Thies , F & Bazinet , R P 2015 , ' Plasma non-esterified docosahexaenoic acid is the major pool supplying the brain : Plasma NEFA pool supplies the brain with DHA ' , Scientific Reports , vol. 5 , 15791 . https://doi.org/10.1038/srep15791en
dc.identifier.issn2045-2322
dc.identifier.otherORCID: /0000-0002-9275-9713/work/99981920
dc.identifier.urihttp://hdl.handle.net/2164/5458
dc.descriptionAcknowledgements This project was funded by a NSERC and CIHR grant to R.P.B. and studentship to C.T.C. R.P.B. holds a Canada Research Chair in Brain Lipid Metabolism. R.P.B. acknowledges support and mass spectrometry equipment and solutions for lipidomics from Sciex. Computer programmable pump software was designed by Dr. Brian Scott. HPLC analyses were performed at the Analytical Facility at the Department of Nutritional Sciences by Dr. Zhen Liu. LC/MS/MS analyses of NEFA-DHA and LPC-DHA and MALDI imaging were performed at the Analytical Facility for Bioactive Molecules (AFBM) with the assistance of Michael Leadley. The AFBM is part of the Centre for the Study of Complex Childhood Diseases (CSCCD) at the Hospital for Sick Children, Toronto, Ontario. CSCCD was supported by Canadian Foundation for Innovation (CFI).en
dc.format.extent12
dc.format.extent1840782
dc.language.isoeng
dc.relation.ispartofScientific Reportsen
dc.subjectDHAen
dc.subjectLPC-DHAen
dc.subjectbrain uptakeen
dc.subjectRC0321 Neuroscience. Biological psychiatry. Neuropsychiatryen
dc.subjectSupplementary Dataen
dc.subject.lccRC0321en
dc.titlePlasma non-esterified docosahexaenoic acid is the major pool supplying the brain : Plasma NEFA pool supplies the brain with DHAen
dc.typeJournal articleen
dc.contributor.institutionUniversity of Aberdeen.Medical Sciences - Cardiovascular Groupen
dc.contributor.institutionUniversity of Aberdeen.Applied Medicineen
dc.contributor.institutionUniversity of Aberdeen.Rowett Instituteen
dc.description.statusPeer revieweden
dc.identifier.doi10.1038/srep15791


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