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A Screenable In Vivo Assay for Mitochondrial Modulators Using Transgenic Bioluminescent Caenorhabditis elegans

dc.contributor.authorLagido, Cristina
dc.contributor.authorMcLaggan, Debbie
dc.contributor.authorGlover, L Anne
dc.date.accessioned2015-12-03T12:52:01Z
dc.date.available2015-12-03T12:52:01Z
dc.date.issued2015
dc.identifier59571671
dc.identifier2b711b5e-16c0-491e-abb9-b933c7192427
dc.identifier26554627
dc.identifier84946423332
dc.identifier.citationLagido , C , McLaggan , D & Glover , L A 2015 , ' A Screenable In Vivo Assay for Mitochondrial Modulators Using Transgenic Bioluminescent Caenorhabditis elegans ' , Journal of visualized experiments : JoVE , no. 104 , e53083 . https://doi.org/10.3791/53083en
dc.identifier.otherORCID: /0000-0003-3947-5380/work/51158500
dc.identifier.urihttp://hdl.handle.net/2164/5281
dc.descriptionAcknowledgements The authors would like to thank David Gray from the Dundee Drug discovery unit for kindly donating firefly luciferase inhibitory compounds DDD00001434, DDD0001477, DDD00000635 and DDD00023047; Tibor Harkani (Medical University of Vienna) for the suggestion of oxaloacetate as a test compound; and Charlie Dear (University of Aberdeen) for illustrations. This work was funded by a BBSRC Pathfinder award (BB/FOF/PF/4/11) and the University of Aberdeen.en
dc.format.extent12
dc.format.extent951067
dc.language.isoeng
dc.relation.ispartofJournal of visualized experiments : JoVEen
dc.subjectSDG 3 - Good Health and Well-beingen
dc.subjectmolecular biologyen
dc.subjectissue 104en
dc.subjectmodel organismsen
dc.subjectcaenorhabditis elegansen
dc.subjectcellular ATPen
dc.subjectbioluminescenceen
dc.subjectfirefly luciferaseen
dc.subjectbiosensorsen
dc.subjectdrug screeningen
dc.subjectelectron transport chainen
dc.subjectcomplex Ien
dc.subjectmitochondriaen
dc.subjectR Medicineen
dc.subjectBiotechnology and Biological Sciences Research Council (BBSRC)en
dc.subjectBB/FOF/PF/4/11en
dc.subject.lccRen
dc.titleA Screenable In Vivo Assay for Mitochondrial Modulators Using Transgenic Bioluminescent Caenorhabditis elegansen
dc.typeJournal articleen
dc.contributor.institutionUniversity of Aberdeen.Applied Medicineen
dc.contributor.institutionUniversity of Aberdeen.Health Economics Research Uniten
dc.contributor.institutionUniversity of Aberdeen.Vice Principalsen
dc.contributor.institutionUniversity of Aberdeen.Institute of Medical Sciencesen
dc.description.statusPeer revieweden
dc.identifier.doi10.3791/53083


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