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Integrated Genomics of Crohn's Disease Risk Variant Identifies a Role for CLEC12A in Antibacterial Autophagy

dc.contributor.authorBegun, Jakob
dc.contributor.authorLassen, Kara G
dc.contributor.authorJijon, Humberto B
dc.contributor.authorBaxt, Leigh A
dc.contributor.authorGoel, Gautam
dc.contributor.authorHeath, Robert J
dc.contributor.authorNg, Aylwin
dc.contributor.authorTam, Jenny M
dc.contributor.authorKuo, Szu-Yu
dc.contributor.authorVillablanca, Eduardo J
dc.contributor.authorFagbami, Lola
dc.contributor.authorOosting, Marije
dc.contributor.authorKumar, Vinod
dc.contributor.authorSchenone, Monica
dc.contributor.authorCarr, Steven A
dc.contributor.authorJoosten, Leo A B
dc.contributor.authorVyas, Jatin M
dc.contributor.authorDaly, Mark J
dc.contributor.authorNetea, Mihai G
dc.contributor.authorBrown, Gordon D
dc.contributor.authorWijmenga, Cisca
dc.contributor.authorXavier, Ramnik J
dc.date.accessioned2015-08-11T10:45:40Z
dc.date.available2015-08-11T10:45:40Z
dc.date.issued2015-06-30
dc.identifier54731188
dc.identifier727b7ede-5c2f-4a87-a00b-c36464452658
dc.identifier26095365
dc.identifier84933675704
dc.identifier.citationBegun , J , Lassen , K G , Jijon , H B , Baxt , L A , Goel , G , Heath , R J , Ng , A , Tam , J M , Kuo , S-Y , Villablanca , E J , Fagbami , L , Oosting , M , Kumar , V , Schenone , M , Carr , S A , Joosten , L A B , Vyas , J M , Daly , M J , Netea , M G , Brown , G D , Wijmenga , C & Xavier , R J 2015 , ' Integrated Genomics of Crohn's Disease Risk Variant Identifies a Role for CLEC12A in Antibacterial Autophagy ' , Cell Reports , vol. 11 , no. 12 , pp. 1905-1918 . https://doi.org/10.1016/j.celrep.2015.05.045en
dc.identifier.issn2211-1247
dc.identifier.urihttp://hdl.handle.net/2164/4802
dc.descriptionCopyright © 2015 The Authors. Published by Elsevier Inc. All rights reserved. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). Acknowledgments We thank Mathieu Platteel (UMCG) for microarray experiments and Natalia Nedelsky for editorial assistance. R.J.X. was supported by the Leona M. and Harry B. Helmsley Charitable Trust, the Crohn’s and Colitis Foundation of America, and grants AI109725 and DK097485 from the NIH. C.W. is supported by funding from the European Research Council under the European Union’s Seventh Framework Programme (FP/2007-2013)/ERC Advanced grant agreement 2012-322698). M.G.N was supported by an ERC Consolidator Grant (no. 310372). G.D.B. was supported by the Wellcome Trust. H.B.J. was supported by a clinical fellowship from Alberta Innovates-Health Solutions (AIHS), Alberta, Canada.en
dc.format.extent14
dc.format.extent4538336
dc.language.isoeng
dc.relation.ispartofCell Reportsen
dc.subjectSDG 3 - Good Health and Well-beingen
dc.subjectR Medicineen
dc.subject.lccRen
dc.titleIntegrated Genomics of Crohn's Disease Risk Variant Identifies a Role for CLEC12A in Antibacterial Autophagyen
dc.typeJournal articleen
dc.contributor.institutionUniversity of Aberdeen.Applied Medicineen
dc.contributor.institutionUniversity of Aberdeen.Institute of Medical Sciencesen
dc.description.statusPeer revieweden
dc.identifier.doi10.1016/j.celrep.2015.05.045


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