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Properties of the mechanosensitive channel MscS pore revealed by tryptophan scanning mutagenesis

dc.contributor.authorRasmussen, Tim
dc.contributor.authorRasmussen, Akiko
dc.contributor.authorSingh, Shivani
dc.contributor.authorGalbiati, Heloisa
dc.contributor.authorEdwards, Michelle D.
dc.contributor.authorMiller, Samantha
dc.contributor.authorBooth, Ian R.
dc.date.accessioned2015-07-30T14:55:01Z
dc.date.available2015-07-30T14:55:01Z
dc.date.issued2015-07
dc.identifier52633695
dc.identifierce71f304-3b8c-4e10-bb01-1627276c3b3a
dc.identifier84938354083
dc.identifier.citationRasmussen , T , Rasmussen , A , Singh , S , Galbiati , H , Edwards , M D , Miller , S & Booth , I R 2015 , ' Properties of the mechanosensitive channel MscS pore revealed by tryptophan scanning mutagenesis ' , Biochemistry , vol. 54 , no. 29 , pp. 4519-4530 . https://doi.org/10.1021/acs.biochem.5b00294en
dc.identifier.issn0006-2960
dc.identifier.otherORCID: /0000-0002-8223-9693/work/76974588
dc.identifier.urihttp://hdl.handle.net/2164/4729
dc.descriptionFunding This work was supported by a Wellcome Trust Programme grant [092552/A/10/Z awarded to I.R.B., S.M., J. H. Naismith (University of St Andrews, St Andrews, U.K.), and S. J. Conway (University of Oxford, Oxford, U.K.)] (T.R. and M.D.E.), by a BBSRC grant (A.R.) [BB/H017917/1 awarded to I.R.B., J. H. Naismith, and O. Schiemann (University of St Andrews)], by a Leverhulme Emeritus Fellowship (EM-2012-060\2), and by a CEMI grant to I.R.B. from the California Institute of Technology. The research leading to these results has received funding from the European Union Seventh Framework Programme (FP7/2007-2013 FP7/2007-2011) under Grant PITN-GA-2011-289384 (FP7-PEOPLE-2011-ITN NICHE) (H.G.) (awarded to S.M.).en
dc.format.extent12
dc.format.extent3966005
dc.language.isoeng
dc.relation.ispartofBiochemistryen
dc.subjectfluorescenceen
dc.subjectbacterial homeostasisen
dc.subjecthypoosmotic shocken
dc.subjectcomplex stabilityen
dc.subjectmembrane proteinen
dc.subjectpore hydrationen
dc.subjectQ Scienceen
dc.subjectWellcome Trusten
dc.subject092552/A/10/Zen
dc.subjectBiotechnology and Biological Sciences Research Council (BBSRC)en
dc.subjectBB/H017917/1 aen
dc.subject.lccQen
dc.titleProperties of the mechanosensitive channel MscS pore revealed by tryptophan scanning mutagenesisen
dc.typeJournal articleen
dc.contributor.institutionUniversity of Aberdeen.Medical Sciencesen
dc.description.statusPeer revieweden
dc.identifier.doi10.1021/acs.biochem.5b00294


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