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Cellular Models of Aggregation-Dependent Template-Directed Proteolysis to Characterize Tau Aggregation Inhibitors for Treatment of Alzheimer's Disease

dc.contributor.authorHarrington, Charles R
dc.contributor.authorStorey, John M D
dc.contributor.authorClunas, Scott
dc.contributor.authorHarrington, Kathleen A
dc.contributor.authorHorsley, David
dc.contributor.authorIshaq, Ahtsham
dc.contributor.authorKemp, Steven J
dc.contributor.authorLarch, Christopher P
dc.contributor.authorMarshall, Colin
dc.contributor.authorNicoll, Sarah L
dc.contributor.authorRickard, Janet E
dc.contributor.authorSimpson, Michael
dc.contributor.authorSinclair, James P
dc.contributor.authorStorey, Lynda J
dc.contributor.authorWischik, Claude M
dc.date.accessioned2015-05-28T13:59:03Z
dc.date.available2015-05-28T13:59:03Z
dc.date.issued2015-04-24
dc.identifier.citationHarrington , C R , Storey , J M D , Clunas , S , Harrington , K A , Horsley , D , Ishaq , A , Kemp , S J , Larch , C P , Marshall , C , Nicoll , S L , Rickard , J E , Simpson , M , Sinclair , J P , Storey , L J & Wischik , C M 2015 , ' Cellular Models of Aggregation-Dependent Template-Directed Proteolysis to Characterize Tau Aggregation Inhibitors for Treatment of Alzheimer's Disease ' , The Journal of Biological Chemistry , vol. 290 , no. 17 , pp. 10862-10875 . https://doi.org/10.1074/jbc.M114.616029en
dc.identifier.issn0021-9258
dc.identifier.otherPURE: 49707206
dc.identifier.otherPURE UUID: 55cb2b04-b245-45ac-b4b6-c9dfd2c706e3
dc.identifier.otherPubMed: 25759392
dc.identifier.otherScopus: 84928401341
dc.identifier.otherORCID: /0000-0002-5261-5467/work/73579095
dc.identifier.urihttp://hdl.handle.net/2164/4569
dc.descriptionCopyright © 2015, The American Society for Biochemistry and Molecular Biology. Acknowledgements-We thank Drs Timo Rager and Rolf Hilfiker (Solvias, Switzerland) for polymorph analyses.en
dc.format.extent14
dc.language.isoeng
dc.relation.ispartofThe Journal of Biological Chemistryen
dc.rightsThis is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. https://creativecommons.org/licenses/by/3.0/en
dc.subjectAlzheimer Diseaseen
dc.subjectcell biologyen
dc.subjectprotein aggregationen
dc.subjecttau protein (tau)en
dc.subjecttauopathyen
dc.subjectLMTXen
dc.subjectprion-like processingen
dc.subjectmethylthioniniumen
dc.subjectQH301 Biologyen
dc.subjectQD Chemistryen
dc.subject.lccQH301en
dc.subject.lccQDen
dc.titleCellular Models of Aggregation-Dependent Template-Directed Proteolysis to Characterize Tau Aggregation Inhibitors for Treatment of Alzheimer's Diseaseen
dc.typeJournal articleen
dc.contributor.institutionUniversity of Aberdeen.Institute of Medical Sciencesen
dc.contributor.institutionUniversity of Aberdeen.Medical Sciencesen
dc.contributor.institutionUniversity of Aberdeen.Chemistryen
dc.contributor.institutionUniversity of Aberdeen.Applied Medicineen
dc.description.statusPeer revieweden
dc.description.versionPublisher PDFen
dc.identifier.doihttps://doi.org/10.1074/jbc.M114.616029


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