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Trained immunity or tolerance : opposing functional programs induced in human monocytes after engagement of various pattern recognition receptors

dc.contributor.authorIfrim, Daniela C
dc.contributor.authorQuintin, Jessica
dc.contributor.authorJoosten, Leo A B
dc.contributor.authorJacobs, Cor
dc.contributor.authorJansen, Trees
dc.contributor.authorJacobs, Liesbeth
dc.contributor.authorGow, Neil A R
dc.contributor.authorWilliams, David L
dc.contributor.authorvan der Meer, Jos W M
dc.contributor.authorNetea, Mihai G
dc.date.accessioned2015-02-04T14:20:01Z
dc.date.available2015-02-04T14:20:01Z
dc.date.issued2014-04
dc.identifier46089106
dc.identifier8322e781-bdb3-4317-983a-7d970c1827da
dc.identifier24521784
dc.identifier84895800375
dc.identifier.citationIfrim , D C , Quintin , J , Joosten , L A B , Jacobs , C , Jansen , T , Jacobs , L , Gow , N A R , Williams , D L , van der Meer , J W M & Netea , M G 2014 , ' Trained immunity or tolerance : opposing functional programs induced in human monocytes after engagement of various pattern recognition receptors ' , Clinical and Vaccine Immunology , vol. 21 , no. 4 , pp. 534-545 . https://doi.org/10.1128/CVI.00688-13en
dc.identifier.issn1556-6811
dc.identifier.urihttp://hdl.handle.net/2164/4235
dc.descriptionArticle Accepted Date: 29 January 2014. ACKNOWLEDGMENTS D.C.I. received funding from the European Union's Seventh Framework Programme (FP7/2007-2013) under grant agreement HEALTH-2010-260338 (“Fungi in the setting of inflammation, allergy and autoimmune diseases: translating basic science into clinical practices” [ALLFUN]) (awarded to M.G.N.). M.G.N. and J.Q. were supported by a Vici grant of the Netherlands Organization of Scientific Research (awarded to M.G.N.). This work was supported, in part, by National Institutes of Health grant GM53522 to D.L.W. N.A.R.G. was supported by the Wellcome Trust.en
dc.format.extent12
dc.format.extent2972095
dc.language.isoeng
dc.relation.ispartofClinical and Vaccine Immunologyen
dc.subjectAntigens, Bacterialen
dc.subjectAntigens, Viralen
dc.subjectBacteriaen
dc.subjectCandida albicansen
dc.subjectCytokinesen
dc.subjectHumansen
dc.subjectImmune Toleranceen
dc.subjectMonocytesen
dc.subjectReceptors, Pattern Recognitionen
dc.subjectVirusesen
dc.subjectQR Microbiologyen
dc.subjectWellcome Trusten
dc.subject.lccQRen
dc.titleTrained immunity or tolerance : opposing functional programs induced in human monocytes after engagement of various pattern recognition receptorsen
dc.typeJournal articleen
dc.contributor.institutionUniversity of Aberdeen.Applied Medicineen
dc.contributor.institutionUniversity of Aberdeen.Medical Sciencesen
dc.description.statusPeer revieweden
dc.identifier.doi10.1128/CVI.00688-13


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