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Tau Aggregation Inhibitor Therapy : An Exploratory Phase 2 Study in Mild or Moderate Alzheimer's Disease

dc.contributor.authorWischik, Claude M
dc.contributor.authorStaff, Roger T
dc.contributor.authorWischik, Damon J
dc.contributor.authorBentham, Peter
dc.contributor.authorMurray, Alison D
dc.contributor.authorStorey, John M D
dc.contributor.authorKook, Karin A
dc.contributor.authorHarrington, Charles R
dc.date.accessioned2015-01-27T10:04:01Z
dc.date.available2015-01-27T10:04:01Z
dc.date.issued2015-01-22
dc.identifier46126219
dc.identifier2de5d671-226c-45f9-8e8d-713ec5683bfe
dc.identifier25550228
dc.identifier84921531217
dc.identifier.citationWischik , C M , Staff , R T , Wischik , D J , Bentham , P , Murray , A D , Storey , J M D , Kook , K A & Harrington , C R 2015 , ' Tau Aggregation Inhibitor Therapy : An Exploratory Phase 2 Study in Mild or Moderate Alzheimer's Disease ' , Journal of Alzheimer's Disease , vol. 44 , no. 2 , pp. 705-720 . https://doi.org/10.3233/JAD-142874en
dc.identifier.issn1387-2877
dc.identifier.otherORCID: /0000-0002-5261-5467/work/73579154
dc.identifier.otherORCID: /0000-0003-4915-4847/work/44018599
dc.identifier.urihttp://hdl.handle.net/2164/4205
dc.descriptionACKNOWLEDGMENTS We thank patients and their caregivers for their participation in the study and are indebted to all the investigators involved in the study, particularly Drs. Douglas Fowlie and Donald Mowat for their helpful contributions to the clinical execution of the study in Scotland. We thank Sharon Eastwood, Parexel, for assistance in preparing initial drafts of the manuscript. We acknowledge constructive comments provided by Professors G. Wilcock and S. Gauthier on drafts of the article. CMW, CRH, and JMDS are officers of, and hold beneficial interests in, TauRx Therapeutics. RTS, PB, KK, and DJW are paid consultants to TauRx Therapeutics. The study was financed entirely by TauRx Therapeuticsen
dc.format.extent16
dc.format.extent630170
dc.language.isoeng
dc.relation.ispartofJournal of Alzheimer's Diseaseen
dc.subjectAlzheimer's diseaseen
dc.subjectcontrolled clinical trialen
dc.subjectintervention studiesen
dc.subjectmethylthioniniumen
dc.subjectsafetyen
dc.subjecttau proteinen
dc.subjectR Medicineen
dc.subjectSupplementary Dataen
dc.subject.lccRen
dc.titleTau Aggregation Inhibitor Therapy : An Exploratory Phase 2 Study in Mild or Moderate Alzheimer's Diseaseen
dc.typeJournal articleen
dc.contributor.institutionUniversity of Aberdeen.Other Applied Health Sciencesen
dc.contributor.institutionUniversity of Aberdeen.Medical Sciencesen
dc.contributor.institutionUniversity of Aberdeen.Applied Medicineen
dc.contributor.institutionUniversity of Aberdeen.Grampian Data Safe Haven (DaSH)en
dc.contributor.institutionUniversity of Aberdeen.Aberdeen Biomedical Imaging Centreen
dc.contributor.institutionUniversity of Aberdeen.Chemistryen
dc.contributor.institutionUniversity of Aberdeen.Institute of Medical Sciencesen
dc.description.statusPeer revieweden
dc.identifier.doi10.3233/JAD-142874


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