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Accuracy and efficiency define Bxb1 integrase as the best of fifteen candidate serine recombinases for the integration of DNA into the human genome

dc.contributor.authorXu, Zhengyao
dc.contributor.authorThomas, Louise
dc.contributor.authorDavies, Ben
dc.contributor.authorChalmers, Ronald
dc.contributor.authorSmith, Maggie
dc.contributor.authorBrown, William
dc.date.accessioned2014-08-28T14:57:01Z
dc.date.available2014-08-28T14:57:01Z
dc.date.issued2013-10-20
dc.identifier40057225
dc.identifier10694fa7-9d13-4bd2-96cd-deddab44b068
dc.identifier000328410500001
dc.identifier84885506325
dc.identifier.citationXu , Z , Thomas , L , Davies , B , Chalmers , R , Smith , M & Brown , W 2013 , ' Accuracy and efficiency define Bxb1 integrase as the best of fifteen candidate serine recombinases for the integration of DNA into the human genome ' , BMC Biotechnology , vol. 13 , 87 . https://doi.org/10.1186/1472-6750-13-87en
dc.identifier.issn1472-6750
dc.identifier.urihttp://hdl.handle.net/2164/3390
dc.descriptionThis is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. This work was supported by BBSRC grant: BB/H005277/1; New recombinases for genome engineering.en
dc.format.extent1439142
dc.language.isoeng
dc.relation.ispartofBMC Biotechnologyen
dc.subjectserine recombinasesen
dc.subjectgenome manipulationen
dc.subjectDNA damageen
dc.subjectsite-specific recombinationen
dc.subjectstreptomyces phage PHI-BT1en
dc.subjectPHI-C31 integraseen
dc.subjectmammalian-cellsen
dc.subjectcassette exchangeen
dc.subjectexcisionen
dc.subjectdirectionalityen
dc.subjectprophageen
dc.subjectTP901-1en
dc.subjectsystemen
dc.subjectT Technologyen
dc.subject.lccTen
dc.titleAccuracy and efficiency define Bxb1 integrase as the best of fifteen candidate serine recombinases for the integration of DNA into the human genomeen
dc.typeJournal articleen
dc.contributor.institutionUniversity of Aberdeen.Medical Sciencesen
dc.description.statusPeer revieweden
dc.identifier.doi10.1186/1472-6750-13-87


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