University of Aberdeen

AURA - Aberdeen University Research Archive

View Item 
  •   AURA Home
  • 5 - All Research
  • All research
  • View Item
  •   AURA Home
  • 5 - All Research
  • All research
  • View Item
  •   AURA Home
  • 5 - All Research
  • All research
  • View Item
      JavaScript is disabled for your browser. Some features of this site may not work without it.

      The PRaCTICaL study of nurse led, intensive care follow-up programmes for improving long term outcomes from critical illness : a pragmatic randomised controlled trial

      View/Open
      Cuthbertson2009.pdf (143.2Kb)
      Publication date
      2009
      Author
      Cuthbertson, Brian
      Rattray, J
      Campbell, Marion Kay
      Gager, M
      Roughton, S
      Smith, A
      Hull, A
      Breeman, S
      Norrie, John David
      Jenkinson, David James
      Hernández, Rodolfo Andrés
      Johnston, Marie
      Wilson, E
      Waldman, C
      PRaCTICaL Study Group
      Metadata
      Show full item record
      Abstract
      Objectives To test the hypothesis that nurse led follow-up programmes are effective and cost effective in improving quality of life after discharge from intensive care. Design A pragmatic, non-blinded, multicentre, randomised controlled trial. Setting Three UK hospitals (two teaching hospitals and one district general hospital). Participants 286 patients aged ≥18 years were recruited after discharge from intensive care between September 2006 and October 2007. Intervention Nurse led intensive care follow-up programmes versus standard care. Main outcome measure(s) Health related quality of life (measured with the SF-36 questionnaire) at 12 months after randomisation. A cost effectiveness analysis was also performed. Results 286 patients were recruited and 192 completed one year follow-up. At 12 months, there was no evidence of a difference in the SF-36 physical component score (mean 42.0 (SD 10.6) v 40.8 (SD 11.9), effect size 1.1 (95% CI −1.9 to 4.2), P=0.46) or the SF-36 mental component score (effect size 0.4 (−3.0 to 3.7), P=0.83). There were no statistically significant differences in secondary outcomes or subgroup analyses. Follow-up programmes were significantly more costly than standard care and are unlikely to be considered cost effective. Conclusions A nurse led intensive care follow-up programme showed no evidence of being effective or cost effective in improving patients’ quality of life in the year after discharge from intensive care. Further work should focus on the roles of early physical rehabilitation, delirium, cognitive dysfunction, and relatives in recovery from critical illness. Intensive care units should review their follow-up programmes in light of these results.
      Citation
      Cuthbertson, B.H., Rattray, J., Campbell, M.K., Gager, M., Roughton, S., Smith, A., Hull, A., Breeman, S., Norrie, J., Jenkinson, D.J., Hernandez, R., Johnston, M., Wilson, E., and Waldman, C., (2009) The PRaCTICaL study of nurse led, intensive care follow-up programmes for improving long term outcomes from critical illness : a pragmatic randomised controlled trial. British Medical Journal, 339(7728):b3723
      URI
      http://hdl.handle.net/2164/316
      DOI
      http://dx.doi.org/10.1136/bmj.b3723
      Collections
      • All research

      Browse

      All of AURACommunities & CollectionsBy Issue DateAuthorsTitlesSubjectsThis CollectionBy Issue DateAuthorsTitlesSubjects
      Top of Page
      • AURA Home
      • Accessibility
      • PURE
      • Digital Resources
      • Library, Special Collections & Museums
      • Take-Down Notice
      • Send Feedback
      • Contact Us
         
       
      Library, Special Collections and Museums logo
      The Sir Duncan Rice Library
      University of Aberdeen
      Bedford Road
      Aberdeen
      AB24 3AA

      Tel: +44 (0)1224 273330
      Email: library@abdn.ac.uk
       
         

      Share and keep up to date

      FacebookTwitterWordpress

      • AURA Home
      • Accessibility
      • PURE
      • Digital Resources
      • Library, Special Collections & Museums
      • Take-Down Notice
      • Send Feedback
      • Contact Us