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Myocardial infarction risk is increased by periodontal pathobionts : a cross-sectional study

dc.contributor.authorJoshi, C
dc.contributor.authorMezincescu, A
dc.contributor.authorGunasekara, M
dc.contributor.authorRudd, A
dc.contributor.authorBotchorichvili, H
dc.contributor.authorSabir, S
dc.contributor.authorDospinescu, C
dc.contributor.authorNoman, A
dc.contributor.authorHogg, D
dc.contributor.authorCherukara, G
dc.contributor.authorMcLernon, D
dc.contributor.authorHijazi, K
dc.contributor.authorDawson, D
dc.date.accessioned2023-03-08T00:08:26Z
dc.date.available2023-03-08T00:08:26Z
dc.date.issued2022-12
dc.identifier218951417
dc.identifierc2331045-e725-45c6-be57-dbaf261afab3
dc.identifier36329042
dc.identifier85141132531
dc.identifier000878770000076
dc.identifier.citationJoshi , C , Mezincescu , A , Gunasekara , M , Rudd , A , Botchorichvili , H , Sabir , S , Dospinescu , C , Noman , A , Hogg , D , Cherukara , G , McLernon , D , Hijazi , K & Dawson , D 2022 , ' Myocardial infarction risk is increased by periodontal pathobionts : a cross-sectional study ' , Scientific Reports , vol. 12 , 18608 . https://doi.org/10.1038/s41598-022-19154-zen
dc.identifier.issn2045-2322
dc.identifier.otherPubMedCentral: PMC9633823
dc.identifier.otherORCID: /0000-0001-8905-2429/work/122953936
dc.identifier.urihttp://aura-test.abdn.ac.uk/handle/2164/19463
dc.descriptionAcknowledgements The authors thank the laboratory and administrative staff at the Institute of Dentistry and the Institute of Medical Sciences of the University of Aberdeen for their help. We are grateful to Dr Pirkko Pussinen (Institute of Dentistry, University of Turku, Finland) for sharing the P. gingivalis-antibody positive serum samples and a detailed ELISA protocol. We would like to thank all Consultant Cardiologists at Aberdeen Royal Infirmary for identifying suitable patients during the acute on-call: Dr Andrew Hannah, Dr Andrew Stewart, Dr Adelle Dawson, Dr Deepak Garg, Dr Paul Broadhurst, Dr Nicola Ryan. Lastly, we are grateful to all the participating patients. Funding: “Periodontal health in patients acutely admitted for myocardial infarction study” was funded by the Elphinstone Award to Dr Hijazi. Dr Dawson is supported by the British Heart Foundation (FS/RTF/20/30009, NH/19/1/34595, PG/18/35/33786, CS/17/4/32960, PG/15/88/31780, PG/17/64/33205), Chest Heart and Stroke Scotland (19/53), Tenovus Scotland (G.18.01), Friends of Anchor and Grampian NHS-Endowments.en
dc.format.extent11
dc.format.extent2012639
dc.language.isoeng
dc.relation.ispartofScientific Reportsen
dc.subjectHumansen
dc.subjectCross-Sectional Studiesen
dc.subjectRNA, Ribosomal, 16S/geneticsen
dc.subjectTroponin Ien
dc.subjectPorphyromonas gingivalisen
dc.subjectMyocardial Infarction/epidemiologyen
dc.subjectDNAen
dc.subjectRK Dentistryen
dc.subjectRC Internal medicineen
dc.subjectBritish Heart Foundationen
dc.subjectFS/RTF/20/30009en
dc.subjectNH/19/1/34595en
dc.subjectPG/18/35/33786en
dc.subjectCS/17/4/32960en
dc.subjectPG/15/88/31780en
dc.subjectPG/17/64/33205en
dc.subjectOtheren
dc.subject19/53en
dc.subjectG.18.01en
dc.subject.lccRKen
dc.subject.lccRCen
dc.titleMyocardial infarction risk is increased by periodontal pathobionts : a cross-sectional studyen
dc.typeJournal articleen
dc.contributor.institutionUniversity of Aberdeen.Medical Sciencesen
dc.contributor.institutionUniversity of Aberdeen.Applied Medicineen
dc.contributor.institutionUniversity of Aberdeen.Institute of Medical Sciencesen
dc.contributor.institutionUniversity of Aberdeen.Medical Educationen
dc.contributor.institutionUniversity of Aberdeen.Medicine, Medical Sciences & Nutritionen
dc.contributor.institutionUniversity of Aberdeen.Dental Educationen
dc.contributor.institutionUniversity of Aberdeen.Other Applied Health Sciencesen
dc.contributor.institutionUniversity of Aberdeen.Centre for Health Data Scienceen
dc.contributor.institutionUniversity of Aberdeen.Grampian Data Safe Haven (DaSH)en
dc.contributor.institutionUniversity of Aberdeen.Medical Statisticsen
dc.contributor.institutionUniversity of Aberdeen.Medical Sciences - Cardiovascular Groupen
dc.description.statusPeer revieweden
dc.identifier.doi10.1038/s41598-022-19154-z


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