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Dysregulation in Subcellular Localization of Myelin Basic Protein mRNA Does Not Result in Altered Myelination in Amyotrophic Lateral Sclerosis.

dc.contributor.authorGregory, Jenna
dc.contributor.authorBarton, Samantha K.
dc.contributor.authorSelvaraj, Bhuvaneish T.
dc.contributor.authorMcDade, Karina
dc.contributor.authorHenstridge, Christopher M.
dc.contributor.authorSpires-Jones, Tara L.
dc.contributor.authorJames, Owen G.
dc.contributor.authorMehta, Arpan R.
dc.contributor.authorStory, David
dc.contributor.authorBurr, Karen
dc.contributor.authorMagnani, Dario
dc.contributor.authorIsaacs, Adrian M.
dc.contributor.authorSmith, Colin
dc.contributor.authorChandran, Siddharthan
dc.date.accessioned2022-07-06T14:35:01Z
dc.date.available2022-07-06T14:35:01Z
dc.date.issued2021-09-21
dc.identifier217891596
dc.identifier70542a63-d9f6-4879-a2e7-7c9089dd900d
dc.identifier85115008496
dc.identifier.citationGregory , J , Barton , S K , Selvaraj , B T , McDade , K , Henstridge , C M , Spires-Jones , T L , James , O G , Mehta , A R , Story , D , Burr , K , Magnani , D , Isaacs , A M , Smith , C & Chandran , S 2021 , ' Dysregulation in Subcellular Localization of Myelin Basic Protein mRNA Does Not Result in Altered Myelination in Amyotrophic Lateral Sclerosis. ' , Frontiers in Neuroscience , vol. 15 , 705306 . https://doi.org/10.3389/fnins.2021.705306en
dc.identifier.issn1662-4548
dc.identifier.otherORCID: /0000-0003-3337-4079/work/112144369
dc.identifier.urihttps://hdl.handle.net/2164/18805
dc.descriptionThe authors would like to thank: (i) the MRC Edinburgh Brain Bank for supplying all post-mortem brain material; (ii) The Scottish MND Clinical Specialist team for discussing and obtaining consent from MND patients for inclusion in these resources; (iii) MND Scotland and the Sylvia Aitken Charitable Trust for funding to CS to help to establish the MND Tissue bank. Work has been funded by the Australian National Health and Medical Research Council and the Australian Research Council (NHMRC-ARC; APP1110040), Medical Research Council (MRC UK; MR/L016400/1), Academy of Medical Sciences (AMS; 210JMG 3102 R45620), Euan MacDonald Centre, MND Scotland, UK Dementia Research Institute, which receives its funding from DRI Ltd., funded by the UK Medical Research Council, Alzheimer’s Society, and Alzheimer’s Research UK, the European Research Council (ERC) under the European Union’s Horizon 2020 Research and Innovation Programme under grant agreement No. 681181 and Royal Society of Edinburgh (CRF). ARM is a Lady Edith Wolfson Clinical Fellow and is jointly funded by the Medical Research Council (MRC) and the Motor Neurone Disease Association (MR/R001162/1). BTS is a Rowling-DRI fellow – administered by the Anne Rowling Regenerative Neurology Clinic (ARRNC), University of Edinburgh.en
dc.format.extent10
dc.format.extent2717418
dc.language.isoeng
dc.relation.ispartofFrontiers in Neuroscienceen
dc.subjectSDG 3 - Good Health and Well-beingen
dc.subjectoligodendrocytesen
dc.subjectRNA traffickingen
dc.subjectmyelinationen
dc.subjectALSen
dc.subjectmyelin basic proteinen
dc.subjectRC0321 Neuroscience. Biological psychiatry. Neuropsychiatryen
dc.subjectSupplementary Dataen
dc.subject.lccRC0321en
dc.titleDysregulation in Subcellular Localization of Myelin Basic Protein mRNA Does Not Result in Altered Myelination in Amyotrophic Lateral Sclerosis.en
dc.typeJournal articleen
dc.contributor.institutionUniversity of Aberdeen.Medical Sciencesen
dc.contributor.institutionUniversity of Aberdeen.Neuroscienceen
dc.description.statusPeer revieweden
dc.identifier.doihttps://doi.org/10.3389/fnins.2021.705306
dc.identifier.urlhttps://www.frontiersin.org/articles/10.3389/fnins.2021.705306/fullen
dc.identifier.vol15en


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