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Eye Movement Patterns Can Distinguish Schizophrenia From the Major Affective Disorders and Healthy Control Subjects

dc.contributor.authorSt Clair, David
dc.contributor.authorMacLennan, Graeme
dc.contributor.authorBeedie, Sara A
dc.contributor.authorNouzová, Eva
dc.contributor.authorLemmon, Helen
dc.contributor.authorRujescu, Dan
dc.contributor.authorBenson, Philip J
dc.contributor.authorMcIntosh, Andrew
dc.contributor.authorNath, Mintu
dc.date.accessioned2022-06-08T11:55:01Z
dc.date.available2022-06-08T11:55:01Z
dc.date.issued2022
dc.identifier216132062
dc.identifier3d1ae2e5-fde6-46ec-819a-61dd90c5f7ba
dc.identifier35669867
dc.identifier85133540273
dc.identifier.citationSt Clair , D , MacLennan , G , Beedie , S A , Nouzová , E , Lemmon , H , Rujescu , D , Benson , P J , McIntosh , A & Nath , M 2022 , ' Eye Movement Patterns Can Distinguish Schizophrenia From the Major Affective Disorders and Healthy Control Subjects ' , Schizophrenia Bulletin Open , vol. 3 , no. 1 , sgac032 . https://doi.org/10.1093/schizbullopen/sgac032en
dc.identifier.issn2632-7899
dc.identifier.otherBibtex: 10.1093/schizbullopen/sgac032
dc.identifier.otherORCID: /0000-0002-1039-5646/work/114165175
dc.identifier.urihttps://hdl.handle.net/2164/18695
dc.descriptionOpen Access under the OUP Agreement Funding This project was supported by the following grants: The Royal Society of London, Chief Scientist Office Scotland (CZB/4/734), NHS Grampian Tenovus Scotland (G12/31), NHS Grampian Endowment Fund, Miller MacKenzie Trust, EU-FP6 (SGENE) and Health Innovation Challenge Fund, jointly from Wellcome Trust and Department of Health (WT-103911/Z/14/Z). The funders had no role in the original study design, the ongoing data collection and analysis, interpretation, or writing of the manuscript. We thank all who helped with clinical aspects of the study including research assistants Barbara Duff, Kate Cotton, Foteini Okonomitsiou, Elizabeth Hannaford, Zsuszanna Nemeth and Joanna Rodzinko Paska as well as the patients and volunteers whose help was indispensable. P Benson and D St Clair are co-founders of SACCADE Diagnostics Ltd a spin out company tasked to develop eye movement technology to assist diagnosis of major mental health disorders. The University of Aberdeen has patents pending in Europe (PCT/GB2013/050016) and USA (14/370,611). The data reported in this paper arose solely from funding by the acknowledged UK research bodies and charities none of whom have vested interests in the company. David St Clair had full access to all the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis. Design of study and development of protocols: D St Clair, P Benson and S Beedie. Recruitment of patients, case note review and clinical and eye movement data collection, quality control and feature extraction of eye movement variables: St Clair, Rujescu, MacIntosh, Beedie, Lemmon, Nouzova. Drafting of the manuscript: St Clair and Nath. Critical revision of manuscript for important intellectual content: all authors. Statistical analyses: Nath and Benson. Interpretation of results: Nath, Benson, MacLennan and St Clair. Obtained funding: St Clair, Benson, MacIntosh, Rujescu. Supervision: St Clair, Benson, MacIntosh, Nath, Rujescu.en
dc.format.extent10
dc.format.extent673413
dc.language.isoeng
dc.relation.ispartofSchizophrenia Bulletin Openen
dc.subjecteye movementen
dc.subjectschizophreniaen
dc.subjectaffective disorderen
dc.subjectbiomarkeren
dc.subjectpredictive modellingen
dc.subjectR Medicineen
dc.subjectChief Scientist Office (CSO)en
dc.subjectCZB/4/734en
dc.subjectOtheren
dc.subjectWellcome Trusten
dc.subjectWT-103911/Z/14/Zen
dc.subjectSupplementary Informationen
dc.subject.lccRen
dc.titleEye Movement Patterns Can Distinguish Schizophrenia From the Major Affective Disorders and Healthy Control Subjectsen
dc.typeJournal articleen
dc.contributor.institutionUniversity of Aberdeen.Applied Medicineen
dc.contributor.institutionUniversity of Aberdeen.Health Services Research Uniten
dc.contributor.institutionUniversity of Aberdeen.Institute of Applied Health Sciencesen
dc.contributor.institutionUniversity of Aberdeen.Psychologyen
dc.contributor.institutionUniversity of Aberdeen.Psychologyen
dc.contributor.institutionUniversity of Aberdeen.Dental Educationen
dc.contributor.institutionUniversity of Aberdeen.Other Applied Health Sciencesen
dc.contributor.institutionUniversity of Aberdeen.Medical Statisticsen
dc.description.statusPeer revieweden
dc.identifier.doi10.1093/schizbullopen/sgac032
dc.identifier.urlhttps://doi.org/10.1093/schizbullopen/sgac032en


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