dc.contributor.author | De Verteuil, Robyn | en |
dc.contributor.author | Hernández, Rodolfo Andrés | en |
dc.contributor.author | Vale, Luke David | en |
dc.contributor.author | Aberdeen Health Technology Assessment Group | en |
dc.date.accessioned | 2007-11-16T14:17:56Z | |
dc.date.available | 2007-11-16T14:17:56Z | |
dc.date.issued | 2007 | |
dc.identifier.citation | de Verteuil, R., Hernandez, R., and Vale, L. (2007). Economic evaluation of laparoscopic surgery for colorectal cancer. International Journal of Technology Assessment in Health Care, 23(4), pp.464-472. | en |
dc.identifier.issn | 0266-4623 | |
dc.identifier.other | PURE: 349888 | en |
dc.identifier.uri | http://hdl.handle.net/2164/172 | |
dc.description.abstract | Objectives: To assess the cost-effectiveness of laparoscopic surgery compared with open surgery for the treatment of colorectal cancer. Methods: A Markov model was developed to model cost-effectiveness over 25 years. Data on the clinical effectiveness of laparoscopic and open surgery for colorectal cancer were obtained from a systematic review of the literature. Data on costs came from a systematic review of economic evaluations and from published sources. The outcomes of the model were presented as the incremental cost per life year gained and using cost-effectiveness acceptability curves (CEACs) to illustrate the likelihood that a treatment was cost-effective at various threshold values for society’s willingness to pay for an additional life year. Results: Laparoscopic surgery was on average £300 more costly and slightly less effective than open surgery and had a 30% chance of being cost-effective if society is willing to pay £30,000 for a life year. One interpretation of the available data suggests equal survival and disease-free survival. Making this assumption, laparoscopic surgery had a greater chance of being considered cost-effective. Presenting the results as incremental cost per quality adjusted life year (QALY) made no difference to the results, as utility data were poor. Evidence suggests short-term benefits following laparoscopic repair. This benefit would have to be at least 0.01 of a QALY for laparoscopic surgery to be considered cost-effective.
Conclusions: Laparoscopic surgery is likely to be associated with short-term quality of life benefits, similar long-term outcomes and an additional £300 per patient. A judgement is required as to whether the short-term benefits are worth this extra cost. | en |
dc.format.extent | 737792 bytes | |
dc.format.mimetype | application/msword | |
dc.language.iso | en | en |
dc.publisher | Cambridge University Press | en |
dc.subject | Colorectal Neoplasma | en |
dc.subject | Economic Evaluation | en |
dc.subject | Laparoscopy | en |
dc.subject | Cost-effectiveness | en |
dc.subject | Markov modelling | en |
dc.subject | Colorectal cancer | en |
dc.subject | Systematic Review | en |
dc.subject.lcc | RC Internal medicine | en |
dc.title | Economic evaluation of laparoscopic surgery for colorectal cancer | en |
dc.type | Journal Article | en |
dc.type | Text | en |
dc.contributor.institution | University of Aberdeen, School of Medicine & Dentistry, Division of Applied Health Sciences | en |
dc.description.status | Peer reviewed | en |
dc.description.version | Author version | en |
dc.identifier.doi | http://dx.doi.org/10.1017/S0266462307070559 | |