Show simple item record

DNA methylation meta-analysis reveals cellular alterations in psychosis and markers of treatment-resistant schizophrenia

dc.contributor.authorHannon, Eilis
dc.contributor.authorDempster, Emma L.
dc.contributor.authorMansell, Georgina
dc.contributor.authorBurrage, Joe
dc.contributor.authorBass, Nick
dc.contributor.authorBohlken, Marc M.
dc.contributor.authorCorvin, Aiden
dc.contributor.authorCurtis, Charles J.
dc.contributor.authorDempster, David
dc.contributor.authorDi Forti, Marta
dc.contributor.authorDinan, Timothy G.
dc.contributor.authorDonohoe, Gary
dc.contributor.authorGaughran, Fiona
dc.contributor.authorGill, Michael
dc.contributor.authorGillespie, Amy
dc.contributor.authorGunasinghe, Cerisse
dc.contributor.authorHulshoff, Hilleke E.
dc.contributor.authorHultman, Christina M.
dc.contributor.authorJohansson, Viktoria
dc.contributor.authorKahn, Rene S.
dc.contributor.authorKaprio, Jaakko
dc.contributor.authorKenis, Gunter
dc.contributor.authorKowalec, Kaarina
dc.contributor.authorMaccabe, James
dc.contributor.authorMcDonald, Colm
dc.contributor.authorMcQuillin, Andew
dc.contributor.authorMorris, Derek W.
dc.contributor.authorMurphy, Kieran C.
dc.contributor.authorMustard, Collette
dc.contributor.authorNenadic, Igor
dc.contributor.authorO'donovan, Michael C.
dc.contributor.authorQuattrone, Diego
dc.contributor.authorRichards, Alexander L.
dc.contributor.authorRutten, Bart P.F.
dc.contributor.authorSt Clair, David
dc.contributor.authorTherman, Sebastian
dc.contributor.authorToulopoulou, Timothea
dc.contributor.authorVan Os, Jim
dc.contributor.authorWaddington, John L.
dc.contributor.authorWellcome Trust Case Control Consortium 2
dc.contributor.authorCRESTAR consortium
dc.contributor.authorSullivan, Patrick
dc.contributor.authorVassos, Evangelos
dc.contributor.authorBreen, Gerome
dc.contributor.authorCollier, David Andrew
dc.contributor.authorMurray, Robin
dc.contributor.authorSchalkwyk, Leonard S.
dc.contributor.authorMill, Jonathan
dc.date.accessioned2021-04-15T13:08:01Z
dc.date.available2021-04-15T13:08:01Z
dc.date.issued2021-02-26
dc.identifier190694852
dc.identifierdde6b690-e38f-490d-b643-28795be26e3b
dc.identifier85101932123
dc.identifier.citationHannon , E , Dempster , E L , Mansell , G , Burrage , J , Bass , N , Bohlken , M M , Corvin , A , Curtis , C J , Dempster , D , Di Forti , M , Dinan , T G , Donohoe , G , Gaughran , F , Gill , M , Gillespie , A , Gunasinghe , C , Hulshoff , H E , Hultman , C M , Johansson , V , Kahn , R S , Kaprio , J , Kenis , G , Kowalec , K , Maccabe , J , McDonald , C , McQuillin , A , Morris , D W , Murphy , K C , Mustard , C , Nenadic , I , O'donovan , M C , Quattrone , D , Richards , A L , Rutten , B P F , St Clair , D , Therman , S , Toulopoulou , T , Van Os , J , Waddington , J L , Wellcome Trust Case Control Consortium 2 , CRESTAR consortium , Sullivan , P , Vassos , E , Breen , G , Collier , D A , Murray , R , Schalkwyk , L S & Mill , J 2021 , ' DNA methylation meta-analysis reveals cellular alterations in psychosis and markers of treatment-resistant schizophrenia ' , eLife , vol. 10 , e58430 . https://doi.org/10.7554/eLife.58430en
dc.identifier.urihttps://hdl.handle.net/2164/16252
dc.descriptionFunding Information: This work was primarily supported by grants from the UK Medical Research Council (MRC; MR/K013807/1 and MR/R005176/1) to J.M. High-performance computing was supported by MRC Clinical Research Infrastructure Funding (MR/M008924/1). The Finnish Twin study was supported by the Academy of Finland Centre of Excellence in Complex Disease Genetics (grant numbers: 213506, 129680), and J.K. by the Academy of Finland grants 265240, 263278 and 312073. Financial support for the Sweden twin study was provided by the Karolinska Institutet (ALF 20090183 and ALF 20100305 to Hultman) and NIH (R01 MH52857). Collection of the Sweden case control samples was supported by the Sweden Research Council (Vetenskapsra?det, award D0886501 to PFS) and the NIMH (R01MH077139). Collection of the Irish case control samples was funded by the Wellcome Trust Case Control Consortium 2 project (085475/B/08/Z and 085475/Z/08/Z), the Wellcome Trust (072894/Z/03/Z, 090532/Z/09/Z and 075491/Z/04/B), and Science Foundation Ireland (08/IN.1/B1916). The European Network of National Schizophrenia Networks Studying Gene-Environment Interactions (EU-GEI) Project is funded by grant agreement HEALTH-F2-2010-241909 (Project EU-GEI) from the European Community's Seventh Framework Programme. The IMPaCT programme at King's College London and the South London and Maudsley NHS Foundation Trust is funded by the National Institute for Health Research (RP-PG-0606-1049). The CRESTAR project received funding from the European Union's Seventh Framework Programme for research, technological development and demonstration under grant agreement 279227 (CRET AR Consortium). EH, ED, LS and JM were supported by MRC grant K013807 to JM. Cardiff University researchers were supported by Medical Research Council (MRC) Centre (G0800509) and Programme Grant (G0801418). Bart PF Rutten is supported by a VIDI grant (number 91718336) from the Netherlands Organisation for Scientific Research. FG is in part supported by the National Institute for Health Research (NIHR) Biomedical Research Centre at South London and Maudsley NHS Foundation Trust and King's College London, the Stanley Medical Research Institute, the Maudsley Charity and the National Institute for Health Research (NIHR) Applied Research Collaboration South London (NIHR ARC South London) at King's College Hospital NHS Foundation Trust. MDF and DQ are funded by an MRC fellowship to MDF (MR/M008436/1). We gratefully acknowledge capital equipment funding from the Maudsley Charity (Grant Ref. 980) and Guy's and St Thomas's Charity (Grant Ref. R130505). This study presents independent research supported by the National Institute for Health Research NIHR BioResource Centre Maudsley at South London and Maudsley NHS Foundation Trust and King's College London. The views expressed are those of the author(s) and not necessarily those of the NHS, NIHR, Department of Health and Social Care or King's College London.en
dc.format.extent31
dc.format.extent1365620
dc.language.isoeng
dc.relation.ispartofeLifeen
dc.subjectR Medicineen
dc.subjectGeneral Neuroscienceen
dc.subjectGeneral Immunology and Microbiologyen
dc.subjectGeneral Biochemistry,Genetics and Molecular Biologyen
dc.subjectMedical Research Council (MRC)en
dc.subjectMR/K013807/1en
dc.subjectMR/R005176/1en
dc.subjectMR/M008924/1en
dc.subjectK013807en
dc.subjectMR/M008436/1en
dc.subjectOtheren
dc.subjectNational Institute for Health Research (NIHR)en
dc.subjectR01 MH52857en
dc.subjectRP-PG-0606-1049en
dc.subjectWellcome Trusten
dc.subject072894/Z/03/Zen
dc.subject090532/Z/09/Zen
dc.subject075491/Z/04/Ben
dc.subjectEuropean Commissionen
dc.subjectHEALTH-F2-2010-241909en
dc.subject279227en
dc.subject.lccRen
dc.titleDNA methylation meta-analysis reveals cellular alterations in psychosis and markers of treatment-resistant schizophreniaen
dc.typeJournal articleen
dc.contributor.institutionUniversity of Aberdeen.Applied Medicineen
dc.contributor.institutionUniversity of Aberdeen.Institute of Medical Sciencesen
dc.description.statusPeer revieweden
dc.identifier.doi10.7554/eLife.58430
dc.identifier.urlhttp://www.scopus.com/inward/record.url?scp=85101932123&partnerID=8YFLogxKen


Files in this item

Thumbnail
Name:
Hannon_etal_DNA_methylation_me ...
Size:
1.302Mb
Format:
PDF
View/Open

This item appears in the following Collection(s)

Show simple item record