Show simple item record

Pivotal roles for pH, lactate and lactate-utilizing bacteria in the stability of a human colonic microbial ecosystem

dc.contributor.authorWang, Shui Ping
dc.contributor.authorRubio, Luis A.
dc.contributor.authorDuncan, Sylvia H.
dc.contributor.authorDonachie, Gillian E.
dc.contributor.authorHoltrop, Grietje
dc.contributor.authorLo, Galiana
dc.contributor.authorFarquharson, Freda M.
dc.contributor.authorWagner, Josef
dc.contributor.authorParkhill, Julian
dc.contributor.authorLouis, Petra
dc.contributor.authorWalker, Alan
dc.contributor.authorFlint, Harry J.
dc.date.accessioned2020-10-19T15:31:00Z
dc.date.available2020-10-19T15:31:00Z
dc.date.issued2020-09-08
dc.identifier174316102
dc.identifierb7ba7703-4256-46be-aec6-e31d4cd6ecd7
dc.identifier32900872
dc.identifier85092055623
dc.identifier000579368300014
dc.identifier.citationWang , S P , Rubio , L A , Duncan , S H , Donachie , G E , Holtrop , G , Lo , G , Farquharson , F M , Wagner , J , Parkhill , J , Louis , P , Walker , A & Flint , H J 2020 , ' Pivotal roles for pH, lactate and lactate-utilizing bacteria in the stability of a human colonic microbial ecosystem ' , mSystems , vol. 5 , no. 5 , e00645-20 . https://doi.org/10.1128/mSystems.00645-20en
dc.identifier.issn2379-5077
dc.identifier.otherORCID: /0000-0003-2115-2399/work/80462165
dc.identifier.otherORCID: /0000-0002-4903-0978/work/80462927
dc.identifier.otherORCID: /0000-0001-5099-8495/work/80463414
dc.identifier.urihttps://hdl.handle.net/2164/15248
dc.descriptionACKNOWLEDGEMENTS: The authors would like to thank Donna Henderson for carrying out GC analysis, and Dr Helen Kettle for help with microPop. Thanks also to the Wellcome Sanger Institute’s core sequencing team and CGEBM at the University of Aberdeen for carrying out the Illumina MiSeq sequencing of 16S rRNA genes. The authors would also like to acknowledge the support of the Maxwell compute cluster funded by the University of Aberdeen.en
dc.format.extent18
dc.format.extent3622636
dc.language.isoeng
dc.relation.ispartofmSystemsen
dc.subjectSDG 3 - Good Health and Well-beingen
dc.subjectLactateen
dc.subjectLactate-utilizing bacteriaen
dc.subjectpHen
dc.subjectShort chain fatty acidsen
dc.subjectMathematical modellingen
dc.subjectShort-chain fatty acidsen
dc.subjectPHen
dc.subjectMathematical modelingen
dc.subjectMETABOLITESen
dc.subjectPOPULATIONSen
dc.subjectCOMMUNITIESen
dc.subjectlactate-utilizing bacteriaen
dc.subjectPROPIONATEen
dc.subjectSHORT-BOWEL SYNDROMEen
dc.subjectCHAIN FATTY-ACIDSen
dc.subjectmathematical modelingen
dc.subjectFERMENTATIONen
dc.subjectEUBACTERIUM-HALLIIen
dc.subjectBUTYRATEen
dc.subjectlactateen
dc.subjectshort-chain fatty acidsen
dc.subjectTOOLen
dc.subjectR Medicineen
dc.subjectGeneticsen
dc.subjectEcology, Evolution, Behavior and Systematicsen
dc.subjectMolecular Biologyen
dc.subjectPhysiologyen
dc.subjectBiochemistryen
dc.subjectComputer Science Applicationsen
dc.subjectMicrobiologyen
dc.subjectModelling and Simulationen
dc.subjectSupplementary Dataen
dc.subject.lccRen
dc.titlePivotal roles for pH, lactate and lactate-utilizing bacteria in the stability of a human colonic microbial ecosystemen
dc.typeJournal articleen
dc.contributor.institutionUniversity of Aberdeen.Rowett Instituteen
dc.contributor.institutionUniversity of Aberdeen.Medicine, Medical Sciences & Nutritionen
dc.description.statusPeer revieweden
dc.identifier.doihttps://doi.org/10.1128/mSystems.00645-20
dc.identifier.urlhttp://www.scopus.com/inward/record.url?scp=85092055623&partnerID=8YFLogxKen
dc.identifier.vol5en
dc.identifier.iss5en


Files in this item

Thumbnail
Name:
Wang_etal_Mystems_Pivotal_Role ...
Size:
3.454Mb
Format:
PDF
View/Open

This item appears in the following Collection(s)

Show simple item record