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Sodium bicarbonate to improve physical function in patients over 60 years with advanced chronic kidney disease : the BiCARB RCT

dc.contributor.authorWitham, Miles D.
dc.contributor.authorBand, Margaret
dc.contributor.authorChong, Huey Yi
dc.contributor.authorDonnan, Peter T.
dc.contributor.authorHampson, Geeta
dc.contributor.authorHu, May Khei
dc.contributor.authorLittleford, Roberta C
dc.contributor.authorLamb, Edmund
dc.contributor.authorKalra, Philip
dc.contributor.authorKennedy, Gwen
dc.contributor.authorMcNamee, Paul
dc.contributor.authorPlews, Deirdre
dc.contributor.authorRauchhaus, Petra
dc.contributor.authorSoiza, Roy L
dc.contributor.authorSumukadas, Deepa
dc.contributor.authorWarwick, Graham
dc.contributor.authorAvenell, Alison
dc.date.accessioned2020-06-23T10:10:02Z
dc.date.available2020-06-23T10:10:02Z
dc.date.issued2020-06-01
dc.identifier171212186
dc.identifierb19fcd80-cc4d-4445-abcd-bcdc4621f0a5
dc.identifier32568065
dc.identifier85086871651
dc.identifier000541706500001
dc.identifier.citationWitham , M D , Band , M , Chong , H Y , Donnan , P T , Hampson , G , Hu , M K , Littleford , R C , Lamb , E , Kalra , P , Kennedy , G , McNamee , P , Plews , D , Rauchhaus , P , Soiza , R L , Sumukadas , D , Warwick , G & Avenell , A 2020 , ' Sodium bicarbonate to improve physical function in patients over 60 years with advanced chronic kidney disease : the BiCARB RCT ' , Health Technology Assessment , vol. 24 , no. 27 , pp. 1-120 . https://doi.org/10.3310/hta24270en
dc.identifier.issn1366-5278
dc.identifier.urihttps://hdl.handle.net/2164/14558
dc.descriptionAcknowledgements: We would like to acknowledge the support received from the NHS Scotland Support for Science scheme and the NIHR Renal and Ageing Comprehensive Research Networks; the work of all the investigators, research nurses and study teams at the different sites and the Tayside CTU staff; and, most importantly, all those with kidney disease who participated in the trial. In addition, we acknowledge the support and advice that we received from the independent TSC members (Professor David Stott, Professor Patrick Mark, Professor Tahir Masud and Mr Alex Stephen) and the independent DMC members (Professor Alex McConnachie, Professor David Wheeler, Dr Nicosha de Souza and Dr Andrew Clegg). Professor Marion McMurdo and Dr Simon Ogston were co-applicants on the original proposal, but demitted from the project on retirement and were not involved in the creation of this report. Trial registration: Current Controlled Trials ISRCTN09486651 and EudraCT 2011-005271-16. The systematic review is registered as PROSPERO CRD42018112908. Funding: This project was funded by the National Institute for Health Research (NIHR) Health Technology Assessment programme and will be published in full in Health Technology Assessment; Vol. 24, No. 27. See the NIHR Journals Library website for further project information.en
dc.format.extent120
dc.format.extent3041682
dc.language.isoeng
dc.relation.ispartofHealth Technology Assessmenten
dc.subjectSDG 3 - Good Health and Well-beingen
dc.subjectACIDOSISen
dc.subjectCHRONICen
dc.subjectRANDOMISED CONTROLLED TRIALen
dc.subjectRENAL INSUFFICIENCYen
dc.subjectSODIUM BICARBONATEen
dc.subjectLOWER-EXTREMITY FUNCTIONen
dc.subjectSERUM BICARBONATEen
dc.subjectGLOMERULAR-FILTRATION-RATEen
dc.subjectOLDER-PEOPLEen
dc.subjectMETABOLIC-ACIDOSISen
dc.subjectHEALTHen
dc.subjectQUALITY-OF-LIFEen
dc.subjectASSOCIATIONen
dc.subjectCKDen
dc.subjectPERFORMANCE-MEASURESen
dc.subjectR Medicine (General)en
dc.subjectHealth Policyen
dc.subjectNational Institute for Health Research (NIHR)en
dc.subject10/71/01en
dc.subjectSupplementary Dataen
dc.subject.lccR1en
dc.titleSodium bicarbonate to improve physical function in patients over 60 years with advanced chronic kidney disease : the BiCARB RCTen
dc.typeJournal articleen
dc.contributor.institutionUniversity of Aberdeen.Health Economics Research Uniten
dc.contributor.institutionUniversity of Aberdeen.Medical Educationen
dc.contributor.institutionUniversity of Aberdeen.Institute of Applied Health Sciencesen
dc.contributor.institutionUniversity of Aberdeen.Health Services Research Uniten
dc.description.statusPeer revieweden
dc.identifier.doi10.3310/hta24270
dc.identifier.urlhttp://www.scopus.com/inward/record.url?scp=85086871651&partnerID=8YFLogxKen


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