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Scc2 Is a Potent Activator of Cohesin’s ATPase that Promotes Loading by Binding Scc1 without Pds5

dc.contributor.authorPetela, Naomi J.
dc.contributor.authorGligoris, Thomas G.
dc.contributor.authorMetson, Jean
dc.contributor.authorLee, Byung-Gil
dc.contributor.authorVoulgaris, Menelaos
dc.contributor.authorHu, Bin
dc.contributor.authorKikuchi, Sotaro
dc.contributor.authorChapard, Christophe
dc.contributor.authorChen, Wentao
dc.contributor.authorRajendra, Eeson
dc.contributor.authorSrinivisan, Madhusudhan
dc.contributor.authorYu, Hongtao
dc.contributor.authorLöwe, Jan
dc.contributor.authorNasmyth, Kim A.
dc.date.accessioned2020-04-13T15:50:00Z
dc.date.available2020-04-13T15:50:00Z
dc.date.issued2018-06-21
dc.identifier156319416
dc.identifier31c6d4f3-f4b6-4556-83bf-f0a6cd788fc0
dc.identifier29932904
dc.identifierPMC6028919
dc.identifier85048582420
dc.identifier.citationPetela , N J , Gligoris , T G , Metson , J , Lee , B-G , Voulgaris , M , Hu , B , Kikuchi , S , Chapard , C , Chen , W , Rajendra , E , Srinivisan , M , Yu , H , Löwe , J & Nasmyth , K A 2018 , ' Scc2 Is a Potent Activator of Cohesin’s ATPase that Promotes Loading by Binding Scc1 without Pds5 ' , Molecular Cell , vol. 70 , no. 6 , pp. 1134-1148.e7 . https://doi.org/10.1016/j.molcel.2018.05.022en
dc.identifier.issn1097-2765
dc.identifier.otherORCID: /0000-0001-6316-2830/work/50934077
dc.identifier.urihttps://hdl.handle.net/2164/14051
dc.descriptionAcknowledgements We are grateful to Adele Marston for sharing yeast strains; Peter West for programming support; and Tatiana Wilson, Isobel Johns, and Stefanos Skylakakis for invaluable technical assistance. We thank all members of the Nasmyth group for valuable discussions. This work was funded by Cancer Research UK (C573/A12386 to K.A.N.), the Wellcome Trust (107935/Z/15/Z to K.A.N., 202062/Z/16/Z to B.H., and 202754/Z/16/Z to J.L.), the Medical Research Council (MR/L018047/1 to K.A.N. and U105184326 to J.L.), the European Research Council (294401 to K.A.N.), and the Welch Foundation (I-1441 to H.Y.). H.Y. is an Investigator with the Howard Hughes Medical Institute.en
dc.format.extent23
dc.format.extent7274108
dc.language.isoeng
dc.relation.ispartofMolecular Cellen
dc.subjectSDG 3 - Good Health and Well-beingen
dc.subjectcohesinen
dc.subjectScc2en
dc.subjectPds5en
dc.subjectScc1en
dc.subjectcohesionen
dc.subjectATPaseen
dc.subjectloadingen
dc.subjectHAWKsen
dc.subjectR Medicine (General)en
dc.subjectCancer Research UKen
dc.subjectC573/A12386en
dc.subjectWellcome Trusten
dc.subject107935/Z/15/Zen
dc.subject202062/Z/16/Zen
dc.subject202754/Z/16/Zen
dc.subjectMedical Research Council (MRC)en
dc.subjectMR/L018047/1en
dc.subjectU105184326en
dc.subjectEuropean Research Councilen
dc.subject294401en
dc.subjectOtheren
dc.subjectI-1441en
dc.subjectWelch Foundationen
dc.subjectSupplementary Dataen
dc.subject.lccR1en
dc.titleScc2 Is a Potent Activator of Cohesin’s ATPase that Promotes Loading by Binding Scc1 without Pds5en
dc.typeJournal articleen
dc.description.statusPeer revieweden
dc.identifier.doi10.1016/j.molcel.2018.05.022
dc.identifier.urlhttp://europepmc.org/abstract/med/29932904en


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