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Differential Effects of MitoVitE, α-Tocopherol and Trolox on Oxidative Stress, Mitochondrial Function and Inflammatory Signalling Pathways in Endothelial Cells Cultured under Conditions Mimicking Sepsis

dc.contributor.authorMinter, Beverley E
dc.contributor.authorLowes, Damon A
dc.contributor.authorWebster, Nigel R
dc.contributor.authorGalley, Helen F
dc.date.accessioned2020-03-04T11:10:01Z
dc.date.available2020-03-04T11:10:01Z
dc.date.issued2020-02-26
dc.identifier158422390
dc.identifier9dca43ff-aa5e-458c-a510-6cfc12aef9e6
dc.identifier32110961
dc.identifier000524490700046
dc.identifier85085705334
dc.identifier.citationMinter , B E , Lowes , D A , Webster , N R & Galley , H F 2020 , ' Differential Effects of MitoVitE, α-Tocopherol and Trolox on Oxidative Stress, Mitochondrial Function and Inflammatory Signalling Pathways in Endothelial Cells Cultured under Conditions Mimicking Sepsis ' , Antioxidants , vol. 9 , no. 3 , 195 . https://doi.org/10.3390/antiox9030195en
dc.identifier.issn2076-3921
dc.identifier.urihttps://hdl.handle.net/2164/13776
dc.descriptionFunding: This research was funded by The British Journal of Anaesthesia/Royal College of Anaesthetists (PhD studentship to Beverley Minter). Acknowledgments: We are very grateful to Professor M.P. Murphy, MRC Mitochondrial Biology Unit, Wellcome Trust/MRC Building, Hills Road, Cambridge, UK for the generous gift of MitoVitE used in all the experiments, without which this work would not have been possible.en
dc.format.extent14
dc.format.extent767932
dc.language.isoeng
dc.relation.ispartofAntioxidantsen
dc.subjectsepsisen
dc.subjectMitoVitEen
dc.subjectantioxidanten
dc.subjectmitochondriaen
dc.subjectgene expressionen
dc.subjectcytokinesen
dc.subjectmRNAen
dc.subjectVITAMIN-Een
dc.subjectACTIVATIONen
dc.subjectFACTOR-KAPPA-Ben
dc.subjectINTERLEUKIN-6en
dc.subjectDAMAGEen
dc.subjectIN-VITROen
dc.subjectTARGETED ANTIOXIDANTen
dc.subjectSEPTIC SHOCKen
dc.subjectLIPOPOLYSACCHARIDEen
dc.subjectORGAN DYSFUNCTIONen
dc.subjectCytokinesen
dc.subjectAntioxidanten
dc.subjectGene expressionen
dc.subjectMitochondriaen
dc.subjectSepsisen
dc.subjectR Medicineen
dc.subjectMolecular Biologyen
dc.subjectBiochemistryen
dc.subjectPhysiologyen
dc.subjectClinical Biochemistryen
dc.subjectCell Biologyen
dc.subjectSupplementary Dataen
dc.subject.lccRen
dc.titleDifferential Effects of MitoVitE, α-Tocopherol and Trolox on Oxidative Stress, Mitochondrial Function and Inflammatory Signalling Pathways in Endothelial Cells Cultured under Conditions Mimicking Sepsisen
dc.typeJournal articleen
dc.contributor.institutionUniversity of Aberdeen.Medical Sciencesen
dc.contributor.institutionUniversity of Aberdeen.Applied Medicineen
dc.description.statusPeer revieweden
dc.identifier.doi10.3390/antiox9030195
dc.identifier.urlhttp://www.scopus.com/inward/record.url?scp=85085705334&partnerID=8YFLogxKen


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