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Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes

dc.contributor.authorMahajan, Anubha
dc.contributor.authorWessel, Jennifer
dc.contributor.authorWillems, Sara M.
dc.contributor.authorZhao, Wei
dc.contributor.authorRobertson, Neil R.
dc.contributor.authorChu, Audrey Y.
dc.contributor.authorGan, Wei
dc.contributor.authorKitajima, Hidetoshi
dc.contributor.authorTaliun, Daniel
dc.contributor.authorRayner, N. William
dc.contributor.authorGuo, Xiuqing
dc.contributor.authorLu, Yingchang
dc.contributor.authorLi, Man
dc.contributor.authorJensen, Richard A.
dc.contributor.authorHu, Yao
dc.contributor.authorHuo, Shaofeng
dc.contributor.authorLohman, Kurt K.
dc.contributor.authorZhang, Weihua
dc.contributor.authorCook, James P.
dc.contributor.authorPrins, Bram Peter
dc.contributor.authorFlannick, Jason
dc.contributor.authorGrarup, Niels
dc.contributor.authorTrubetskoy, Vassily Vladimirovich
dc.contributor.authorKravic, Jasmina
dc.contributor.authorKim, Young Jin
dc.contributor.authorRybin, Denis V.
dc.contributor.authorYaghootkar, Hanieh
dc.contributor.authorMüller-Nurasyid, Martina
dc.contributor.authorMeidtner, Karina
dc.contributor.authorLi-Gao, Ruifang
dc.contributor.authorVarga, Tibor V.
dc.contributor.authorMarten, Jonathan
dc.contributor.authorLi, Jin
dc.contributor.authorSmith, Albert Vernon
dc.contributor.authorAn, Ping
dc.contributor.authorLigthart, Symen
dc.contributor.authorGustafsson, Stefan
dc.contributor.authorMalerba, Giovanni
dc.contributor.authorDemirkan, Ayse
dc.contributor.authorTajes, Juan Fernandez
dc.contributor.authorSteinthorsdottir, Valgerdur
dc.contributor.authorWuttke, Matthias
dc.contributor.authorLecoeur, Cécile
dc.contributor.authorPreuss, Michael
dc.contributor.authorBielak, Lawrence F.
dc.contributor.authorGraff, Marielisa
dc.contributor.authorHighland, Heather M.
dc.contributor.authorJustice, Anne E.
dc.contributor.authorLiu, Dajiang J.
dc.contributor.authorMarouli, Eirini
dc.contributor.authorPeloso, Gina Marie
dc.contributor.authorWarren, Helen R.
dc.contributor.authorAfaq, Saima
dc.contributor.authorAfzal, Shoaib
dc.contributor.authorAhlqvist, Emma
dc.contributor.authorAlmgren, Peter
dc.contributor.authorAmin, Najaf
dc.contributor.authorBang, Lia B.
dc.contributor.authorBertoni, Alain G.
dc.contributor.authorBombieri, Cristina
dc.contributor.authorBork-Jensen, Jette
dc.contributor.authorBrandslund, Ivan
dc.contributor.authorBrody, Jennifer A.
dc.contributor.authorBurtt, Noël P.
dc.contributor.authorCanouil, Mickaël
dc.contributor.authorChen, Yii-Der Ida
dc.contributor.authorCho, Yoon Shin
dc.contributor.authorChristensen, Cramer
dc.contributor.authorEastwood, Sophie V.
dc.contributor.authorEckardt, Kai-Uwe
dc.contributor.authorFischer, Krista
dc.contributor.authorGambaro, Giovanni
dc.contributor.authorGiedraitis, Vilmantas
dc.contributor.authorGrove, Megan L.
dc.contributor.authorde Haan, Hugoline G.
dc.contributor.authorHackinger, Sophie
dc.contributor.authorHai, Yang
dc.contributor.authorHan, Sohee
dc.contributor.authorTybjærg-Hansen, Anne
dc.contributor.authorHivert, Marie-France
dc.contributor.authorIsomaa, Bo
dc.contributor.authorJäger, Susanne
dc.contributor.authorJørgensen, Marit E.
dc.contributor.authorJørgensen, Torben
dc.contributor.authorKäräjämäki, Annemari
dc.contributor.authorKim, Bong-Jo
dc.contributor.authorKim, Sung Soo
dc.contributor.authorKoistinen, Heikki A.
dc.contributor.authorKovacs, Peter
dc.contributor.authorKriebel, Jennifer
dc.contributor.authorKronenberg, Florian
dc.contributor.authorLäll, Kristi
dc.contributor.authorLange, Leslie A.
dc.contributor.authorLee, Jung-Jin
dc.contributor.authorLehne, Benjamin
dc.contributor.authorLi, Huaixing
dc.contributor.authorLin, Keng-Hung
dc.contributor.authorLinneberg, Allan
dc.contributor.authorLiu, Ching-Ti
dc.contributor.authorLiu, Jun
dc.contributor.authorLoh, Marie
dc.contributor.authorMägi, Reedik
dc.contributor.authorMamakou, Vasiliki
dc.contributor.authorMcKean-Cowdin, Roberta
dc.contributor.authorNadkarni, Girish
dc.contributor.authorNeville, Matt
dc.contributor.authorNielsen, Sune F.
dc.contributor.authorNtalla, Ioanna
dc.contributor.authorPeyser, Patricia A.
dc.contributor.authorRathmann, Wolfgang
dc.contributor.authorRice, Kenneth
dc.contributor.authorRich, Stephen S.
dc.contributor.authorRode, Line
dc.contributor.authorRolandsson, Olov
dc.contributor.authorSchönherr, Sebastian
dc.contributor.authorSelvin, Elizabeth
dc.contributor.authorSmall, Kerrin S.
dc.contributor.authorStančáková, Alena
dc.contributor.authorSurendran, Praveen
dc.contributor.authorTaylor, Kent D.
dc.contributor.authorTeslovich, Tanya M.
dc.contributor.authorThorand, Barbara
dc.contributor.authorThorleifsson, Gudmar
dc.contributor.authorTin, Adrienne
dc.contributor.authorTönjes, Anke
dc.contributor.authorVarbo, Anette
dc.contributor.authorWitte, Daniel R.
dc.contributor.authorWood, Andrew R.
dc.contributor.authorYajnik, Pranav
dc.contributor.authorYao, Jie
dc.contributor.authorYengo, Loïc
dc.contributor.authorYoung, Robin
dc.contributor.authorAmouyel, Philippe
dc.contributor.authorBoeing, Heiner
dc.contributor.authorBoerwinkle, Eric
dc.contributor.authorBottinger, Erwin P.
dc.contributor.authorChowdhury, Rajiv
dc.contributor.authorCollins, Francis S.
dc.contributor.authorDedoussis, George
dc.contributor.authorDehghan, Abbas
dc.contributor.authorDeloukas, Panos
dc.contributor.authorFerrario, Marco M.
dc.contributor.authorFerrières, Jean
dc.contributor.authorFlorez, Jose C.
dc.contributor.authorFrossard, Philippe
dc.contributor.authorGudnason, Vilmundur
dc.contributor.authorHarris, Tamara B.
dc.contributor.authorHeckbert, Susan R.
dc.contributor.authorHowson, Joanna M. M.
dc.contributor.authorIngelsson, Martin
dc.contributor.authorKathiresan, Sekar
dc.contributor.authorKee, Frank
dc.contributor.authorKuusisto, Johanna
dc.contributor.authorLangenberg, Claudia
dc.contributor.authorLauner, Lenore J.
dc.contributor.authorLindgren, Cecilia M.
dc.contributor.authorMännistö, Satu
dc.contributor.authorMeitinger, Thomas
dc.contributor.authorMelander, Olle
dc.contributor.authorMohlke, Karen L.
dc.contributor.authorMoitry, Marie
dc.contributor.authorMorris, Andrew D.
dc.contributor.authorMurray, Alison D.
dc.contributor.authorde Mutsert, Renée
dc.contributor.authorOrho-Melander, Marju
dc.contributor.authorOwen, Katharine R.
dc.contributor.authorPerola, Markus
dc.contributor.authorPeters, Annette
dc.contributor.authorProvince, Michael A.
dc.contributor.authorRasheed, Asif
dc.contributor.authorRidker, Paul M.
dc.contributor.authorRivadineira, Fernando
dc.contributor.authorRosendaal, Frits R.
dc.contributor.authorRosengren, Anders H.
dc.contributor.authorSalomaa, Veikko
dc.contributor.authorSheu, Wayne H.-H.
dc.contributor.authorSladek, Rob
dc.contributor.authorSmith, Blair H.
dc.contributor.authorStrauch, Konstantin
dc.contributor.authorUitterlinden, André G.
dc.contributor.authorVarma, Rohit
dc.contributor.authorWiller, Cristen J.
dc.contributor.authorBlüher, Matthias
dc.contributor.authorButterworth, Adam S.
dc.contributor.authorChambers, John Campbell
dc.contributor.authorChasman, Daniel I.
dc.contributor.authorDanesh, John
dc.contributor.authorvan Duijn, Cornelia
dc.contributor.authorDupuis, Josée
dc.contributor.authorFranco, Oscar H.
dc.contributor.authorFranks, Paul W.
dc.contributor.authorFroguel, Philippe
dc.contributor.authorGrallert, Harald
dc.contributor.authorGroop, Leif
dc.contributor.authorHan, Bok-Ghee
dc.contributor.authorHansen, Torben
dc.contributor.authorHattersley, Andrew T.
dc.contributor.authorHayward, Caroline
dc.contributor.authorIngelsson, Erik
dc.contributor.authorKardia, Sharon L. R.
dc.contributor.authorKarpe, Fredrik
dc.contributor.authorKooner, Jaspal Singh
dc.contributor.authorKöttgen, Anna
dc.contributor.authorKuulasmaa, Kari
dc.contributor.authorLaakso, Markku
dc.contributor.authorLin, Xu
dc.contributor.authorLind, Lars
dc.contributor.authorLiu, Yongmei
dc.contributor.authorLoos, Ruth J. F.
dc.contributor.authorMarchini, Jonathan
dc.contributor.authorMetspalu, Andres
dc.contributor.authorMook-Kanamori, Dennis
dc.contributor.authorNordestgaard, Børge G.
dc.contributor.authorPalmer, Colin N. A.
dc.contributor.authorPankow, James S.
dc.contributor.authorPedersen, Oluf
dc.contributor.authorPsaty, Bruce M.
dc.contributor.authorRauramaa, Rainer
dc.contributor.authorSattar, Naveed
dc.contributor.authorSchulze, Matthias B.
dc.contributor.authorSoranzo, Nicole
dc.contributor.authorSpector, Timothy D.
dc.contributor.authorStefansson, Kari
dc.contributor.authorStumvoll, Michael
dc.contributor.authorThorsteinsdottir, Unnur
dc.contributor.authorTuomi, Tiinamaija
dc.contributor.authorTuomilehto, Jaakko
dc.contributor.authorWareham, Nicholas J.
dc.contributor.authorWilson, James G.
dc.contributor.authorZeggini, Eleftheria
dc.contributor.authorScott, Robert A.
dc.contributor.authorBarroso, Inês
dc.contributor.authorFrayling, Timothy M.
dc.contributor.authorGoodarzi, Mark O.
dc.contributor.authorMeigs, James B.
dc.contributor.authorBoehnke, Michael
dc.contributor.authorSaleheen, Danish
dc.contributor.authorMorris, Andrew P.
dc.contributor.authorRotter, Jerome I.
dc.contributor.authorMcCarthy, Mark I.
dc.date.accessioned2020-03-01T08:45:01Z
dc.date.available2020-03-01T08:45:01Z
dc.date.issued2018-04-30
dc.identifier117781926
dc.identifier49472eb4-35ab-4c9c-99a8-32cb4eb842cc
dc.identifier29632382
dc.identifier85042368356
dc.identifier.citationMahajan , A , Wessel , J , Willems , S M , Zhao , W , Robertson , N R , Chu , A Y , Gan , W , Kitajima , H , Taliun , D , Rayner , N W , Guo , X , Lu , Y , Li , M , Jensen , R A , Hu , Y , Huo , S , Lohman , K K , Zhang , W , Cook , J P , Prins , B P , Flannick , J , Grarup , N , Trubetskoy , V V , Kravic , J , Kim , Y J , Rybin , D V , Yaghootkar , H , Müller-Nurasyid , M , Meidtner , K , Li-Gao , R , Varga , T V , Marten , J , Li , J , Smith , A V , An , P , Ligthart , S , Gustafsson , S , Malerba , G , Demirkan , A , Tajes , J F , Steinthorsdottir , V , Wuttke , M , Lecoeur , C , Preuss , M , Bielak , L F , Graff , M , Highland , H M , Justice , A E , Liu , D J , Marouli , E , Peloso , G M , Warren , H R , Afaq , S , Afzal , S , Ahlqvist , E , Almgren , P , Amin , N , Bang , L B , Bertoni , A G , Bombieri , C , Bork-Jensen , J , Brandslund , I , Brody , J A , Burtt , N P , Canouil , M , Chen , Y-D I , Cho , Y S , Christensen , C , Eastwood , S V , Eckardt , K-U , Fischer , K , Gambaro , G , Giedraitis , V , Grove , M L , de Haan , H G , Hackinger , S , Hai , Y , Han , S , Tybjærg-Hansen , A , Hivert , M-F , Isomaa , B , Jäger , S , Jørgensen , M E , Jørgensen , T , Käräjämäki , A , Kim , B-J , Kim , S S , Koistinen , H A , Kovacs , P , Kriebel , J , Kronenberg , F , Läll , K , Lange , L A , Lee , J-J , Lehne , B , Li , H , Lin , K-H , Linneberg , A , Liu , C-T , Liu , J , Loh , M , Mägi , R , Mamakou , V , McKean-Cowdin , R , Nadkarni , G , Neville , M , Nielsen , S F , Ntalla , I , Peyser , P A , Rathmann , W , Rice , K , Rich , S S , Rode , L , Rolandsson , O , Schönherr , S , Selvin , E , Small , K S , Stančáková , A , Surendran , P , Taylor , K D , Teslovich , T M , Thorand , B , Thorleifsson , G , Tin , A , Tönjes , A , Varbo , A , Witte , D R , Wood , A R , Yajnik , P , Yao , J , Yengo , L , Young , R , Amouyel , P , Boeing , H , Boerwinkle , E , Bottinger , E P , Chowdhury , R , Collins , F S , Dedoussis , G , Dehghan , A , Deloukas , P , Ferrario , M M , Ferrières , J , Florez , J C , Frossard , P , Gudnason , V , Harris , T B , Heckbert , S R , Howson , J M M , Ingelsson , M , Kathiresan , S , Kee , F , Kuusisto , J , Langenberg , C , Launer , L J , Lindgren , C M , Männistö , S , Meitinger , T , Melander , O , Mohlke , K L , Moitry , M , Morris , A D , Murray , A D , de Mutsert , R , Orho-Melander , M , Owen , K R , Perola , M , Peters , A , Province , M A , Rasheed , A , Ridker , P M , Rivadineira , F , Rosendaal , F R , Rosengren , A H , Salomaa , V , Sheu , W H-H , Sladek , R , Smith , B H , Strauch , K , Uitterlinden , A G , Varma , R , Willer , C J , Blüher , M , Butterworth , A S , Chambers , J C , Chasman , D I , Danesh , J , van Duijn , C , Dupuis , J , Franco , O H , Franks , P W , Froguel , P , Grallert , H , Groop , L , Han , B-G , Hansen , T , Hattersley , A T , Hayward , C , Ingelsson , E , Kardia , S L R , Karpe , F , Kooner , J S , Köttgen , A , Kuulasmaa , K , Laakso , M , Lin , X , Lind , L , Liu , Y , Loos , R J F , Marchini , J , Metspalu , A , Mook-Kanamori , D , Nordestgaard , B G , Palmer , C N A , Pankow , J S , Pedersen , O , Psaty , B M , Rauramaa , R , Sattar , N , Schulze , M B , Soranzo , N , Spector , T D , Stefansson , K , Stumvoll , M , Thorsteinsdottir , U , Tuomi , T , Tuomilehto , J , Wareham , N J , Wilson , J G , Zeggini , E , Scott , R A , Barroso , I , Frayling , T M , Goodarzi , M O , Meigs , J B , Boehnke , M , Saleheen , D , Morris , A P , Rotter , J I & McCarthy , M I 2018 , ' Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes ' , Nature Genetics , vol. 50 , no. 4 , pp. 559-571 . https://doi.org/10.1038/s41588-018-0084-1en
dc.identifier.issn1061-4036
dc.identifier.otherRIS: urn:05C8704902DF1BEAFC1AFFEA86566911
dc.identifier.otherORCID: /0000-0003-4915-4847/work/76976572
dc.identifier.urihttps://hdl.handle.net/2164/13762
dc.descriptionSupplementary information is available for this paper at https://doi.org/10.1038/ s41588-018-0084-1. Acknowledgements A full list of acknowledgments appears in the Supplementary Note. Part of this work was conducted using the UK Biobank Resource under application number 9161.en
dc.format.extent13
dc.format.extent1166935
dc.language.isoeng
dc.relation.ispartofNature Geneticsen
dc.subjectSDG 3 - Good Health and Well-beingen
dc.subjectQH426 Geneticsen
dc.subjectSupplementary Dataen
dc.subject.lccQH426en
dc.titleRefining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetesen
dc.typeJournal articleen
dc.contributor.institutionUniversity of Aberdeen.Applied Medicineen
dc.contributor.institutionUniversity of Aberdeen.Grampian Data Safe Haven (DaSH)en
dc.contributor.institutionUniversity of Aberdeen.Aberdeen Biomedical Imaging Centreen
dc.description.statusPeer revieweden
dc.identifier.doihttps://doi.org/10.1038/s41588-018-0084-1
dc.identifier.urlhttps://www.nature.com/authors/policies/license.htmlen
dc.identifier.vol50en
dc.identifier.iss4en


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