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Blood-brain barrier failure as a core mechanism in cerebral small vessel disease and dementia : evidence from a cohort study

dc.contributor.authorWardlaw, Joanna M.
dc.contributor.authorMakin, Stephen J.
dc.contributor.authorValdés Hernández, Maria C.
dc.contributor.authorArmitage, Paul A.
dc.contributor.authorHeye, Anna K.
dc.contributor.authorChappell, Francesca M.
dc.contributor.authorMuñoz-Maniega, Susana
dc.contributor.authorSakka, Eleni
dc.contributor.authorShuler, Kirsten
dc.contributor.authorDennis, Martin S.
dc.contributor.authorThrippleton, Michael J.
dc.date.accessioned2020-02-18T14:50:01Z
dc.date.available2020-02-18T14:50:01Z
dc.date.issued2017-06-01
dc.identifier147313484
dc.identifier7696d48e-56ce-424a-9048-743dceae0eed
dc.identifier85012939147
dc.identifier.citationWardlaw , J M , Makin , S J , Valdés Hernández , M C , Armitage , P A , Heye , A K , Chappell , F M , Muñoz-Maniega , S , Sakka , E , Shuler , K , Dennis , M S & Thrippleton , M J 2017 , ' Blood-brain barrier failure as a core mechanism in cerebral small vessel disease and dementia : evidence from a cohort study ' , Alzheimer's and Dementia , vol. 13 , no. 6 , pp. 634-643 . https://doi.org/10.1016/j.jalz.2016.09.006en
dc.identifier.issn1552-5260
dc.identifier.otherRIS: urn:61418C6A91159747E9DD41B87C692411
dc.identifier.otherRIS: 12071
dc.identifier.otherORCID: /0000-0001-8701-9043/work/76976276
dc.identifier.urihttps://hdl.handle.net/2164/13711
dc.descriptionWe thank the participants, their relatives, and carers for their time and patience in contributing to the study, the staff of NHS Lothian Stroke Services, and the Brain Research Imaging Centre Edinburgh for their assistance in recruiting and assessing the patients. Funding: Wellcome Trust (WT088134/Z/09/A), Row Fogo Charitable Trust, Scottish Funding Council Scottish Imaging Network A Platform for Scientific Excellence collaboration, Age-UK Disconnected Mind Study, NHS Lothian R+D Department, and The Brain Research Imaging Centre Edinburgh (http://www.sbirc.ed.ac.uk/). Conflict of interest: All authors report grants from Wellcome Trust, grants from Row Fogo Charitable Trust, grants from Age UK, and grants from Scottish Funding Council, during the conduct of the study. Role of the funding source: The funders had no role in the planning, execution, analysis of the study, or preparation of the manuscript or decision to submit. The authors hold the data.en
dc.format.extent10
dc.format.extent1664029
dc.language.isoeng
dc.relation.ispartofAlzheimer's and Dementiaen
dc.subjectblood brain barrieren
dc.subjectsmall vessel diseaseen
dc.subjectstrokeen
dc.subjectwhite matter hyperintensitiesen
dc.subjectdementiaen
dc.subjectR Medicineen
dc.subjectWellcome Trusten
dc.subjectWT088134/Z/09/Aen
dc.subjectScottish Funding Councilen
dc.subjectcottish Imaging Network A Platform for Scientific Excellence collaborationen
dc.subjectSupplementary Dataen
dc.subject.lccRen
dc.titleBlood-brain barrier failure as a core mechanism in cerebral small vessel disease and dementia : evidence from a cohort studyen
dc.typeJournal articleen
dc.contributor.institutionUniversity of Aberdeen.Other Applied Health Sciencesen
dc.contributor.institutionUniversity of Aberdeen.Medicine, Medical Sciences & Nutritionen
dc.description.statusPeer revieweden
dc.identifier.doi10.1016/j.jalz.2016.09.006


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