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Polyphosphate co-localizes with factor XII on plateletbound fibrin and augments its plasminogen activator activity

dc.contributor.authorMitchell, Joanne L
dc.contributor.authorLionikiene, Ausra S.
dc.contributor.authorGeorgiev, Georgi
dc.contributor.authorKlemmer, Anja
dc.contributor.authorBrain, Chelsea
dc.contributor.authorKim, Paul Y
dc.contributor.authorMutch, Nicola J.
dc.date.accessioned2019-05-31T10:00:07Z
dc.date.available2019-05-31T10:00:07Z
dc.date.issued2016-12-15
dc.identifier71139719
dc.identifiera44e5a45-3295-4ac6-8db0-f082353ad809
dc.identifier27694320
dc.identifier27694320
dc.identifier85014934464
dc.identifier.citationMitchell , J L , Lionikiene , A S , Georgiev , G , Klemmer , A , Brain , C , Kim , P Y & Mutch , N J 2016 , ' Polyphosphate co-localizes with factor XII on plateletbound fibrin and augments its plasminogen activator activity ' , Blood , vol. 128 , no. 24 , pp. 2834-2845 . https://doi.org/10.1182/blood-2015-10-673285en
dc.identifier.issn0006-4971
dc.identifier.urihttp://hdl.handle.net/2164/12341
dc.descriptionThis work was supported by grants FS/11/2/28579 (N.J.M. & A.S.L) from the British Heart Foundation and by the University of Aberdeen Development Trust (J.L.M. & N.J.M.). P.Y.K is supported by an Early Career Award and New Investigator Fund from the Hamilton Health Sciences. We are grateful to the following students for contributions to the project, Natasha Walker & Thomas Nolan. We also thank both the Microscopy and Histology Core Facility and the Iain Fraser Cytometry Centre at the University of Aberdeen for excellent advice and use of the facilities. We also thank Dr Jeffrey Weitz from McMaster University, Canada for the kind gift of HRG.en
dc.format.extent12
dc.format.extent188413
dc.language.isoeng
dc.relation.ispartofBlooden
dc.subjectplasminogenen
dc.subjectfactor XIIen
dc.subjectpolyphosphateen
dc.subjectfibrinolysisen
dc.subjectfibrinen
dc.subjectplateletsen
dc.subjectR Medicineen
dc.subjectBritish Heart Foundationen
dc.subjectFS/11/2/28579en
dc.subjectSupplementary Dataen
dc.subject.lccRen
dc.titlePolyphosphate co-localizes with factor XII on plateletbound fibrin and augments its plasminogen activator activityen
dc.typeJournal articleen
dc.contributor.institutionUniversity of Aberdeen.Medicine, Medical Sciences & Nutritionen
dc.contributor.institutionUniversity of Aberdeen.Medical Sciences - Cardiovascular Groupen
dc.contributor.institutionUniversity of Aberdeen.Applied Medicineen
dc.contributor.institutionUniversity of Aberdeen.Engineeringen
dc.description.statusPeer revieweden
dc.identifier.doi10.1182/blood-2015-10-673285
dc.date.embargoedUntil2017-12-15
dc.identifier.vol128en
dc.identifier.iss24en


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