Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity
dc.contributor.author | Kilpeläinen, Tuomas O. | |
dc.contributor.author | Bentley, Amy R. | |
dc.contributor.author | Noordam, Raymond | |
dc.contributor.author | Sung, Yun Ju | |
dc.contributor.author | Schwander, Karen | |
dc.contributor.author | Winkler, Thomas W. | |
dc.contributor.author | Jakupović, Hermina | |
dc.contributor.author | Chasman, Daniel I. | |
dc.contributor.author | Manning, Alisa | |
dc.contributor.author | Ntalla, Ioanna | |
dc.contributor.author | Aschard, Hugues | |
dc.contributor.author | Brown, Michael R. | |
dc.contributor.author | de las Fuentes, Lisa | |
dc.contributor.author | Franceschini, Nora | |
dc.contributor.author | Guo, Xiuqing | |
dc.contributor.author | Vojinovic, Dina | |
dc.contributor.author | Aslibekyan, Stella | |
dc.contributor.author | Feitosa, Mary F. | |
dc.contributor.author | Kho, Minjung | |
dc.contributor.author | Musani, Solomon K. | |
dc.contributor.author | Richard, Melissa | |
dc.contributor.author | Wang, Heming | |
dc.contributor.author | Wang, Zhe | |
dc.contributor.author | Bartz, Traci M. | |
dc.contributor.author | Bielak, Lawrence F. | |
dc.contributor.author | Campbell, Archie | |
dc.contributor.author | Dorajoo, Rajkumar | |
dc.contributor.author | Fisher, Virginia | |
dc.contributor.author | Hartwig, Fernando P. | |
dc.contributor.author | Horimoto, Andrea R. V. R. | |
dc.contributor.author | Li, Changwei | |
dc.contributor.author | Lohman, Kurt K. | |
dc.contributor.author | Marten, Jonathan | |
dc.contributor.author | Sim, Xueling | |
dc.contributor.author | Smith, Albert V. | |
dc.contributor.author | Tajuddin, Salman M. | |
dc.contributor.author | Alver, Maris | |
dc.contributor.author | Amini, Marzyeh | |
dc.contributor.author | Boissel, Mathilde | |
dc.contributor.author | Chai, Jin Fang | |
dc.contributor.author | Chen, Xu | |
dc.contributor.author | Divers, Jasmin | |
dc.contributor.author | Evangelou, Evangelos | |
dc.contributor.author | Gao, Chuan | |
dc.contributor.author | Graff, Mariaelisa | |
dc.contributor.author | Harris, Sarah E. | |
dc.contributor.author | He, Meian | |
dc.contributor.author | Hsu, Fang-Chi | |
dc.contributor.author | Jackson, Anne U. | |
dc.contributor.author | Zhao, Jing Hua | |
dc.contributor.author | Kraja, Aldi T. | |
dc.contributor.author | Kühnel, Brigitte | |
dc.contributor.author | Laguzzi, Federica | |
dc.contributor.author | Lyytikäinen, Leo-Pekka | |
dc.contributor.author | Nolte, Ilja M. | |
dc.contributor.author | Rauramaa, Rainer | |
dc.contributor.author | Riaz, Muhammad | |
dc.contributor.author | Robino, Antonietta | |
dc.contributor.author | Rueedi, Rico | |
dc.contributor.author | Stringham, Heather M. | |
dc.contributor.author | Takeuchi, Fumihiko | |
dc.contributor.author | van der Most, Peter J. | |
dc.contributor.author | Varga, Tibor V. | |
dc.contributor.author | Verweij, Niek | |
dc.contributor.author | Ware, Erin B. | |
dc.contributor.author | Wen, Wanqing | |
dc.contributor.author | Li, Xiaoyin | |
dc.contributor.author | Yanek, Lisa R. | |
dc.contributor.author | Amin, Najaf | |
dc.contributor.author | Arnett, Donna K. | |
dc.contributor.author | Boerwinkle, Eric | |
dc.contributor.author | Brumat, Marco | |
dc.contributor.author | Cade, Brian | |
dc.contributor.author | Canouil, Mickaël | |
dc.contributor.author | Chen, Yii-Der Ida | |
dc.contributor.author | Concas, Maria Pina | |
dc.contributor.author | Connell, John | |
dc.contributor.author | de Mutsert, Renée | |
dc.contributor.author | de Silva, H. Janaka | |
dc.contributor.author | de Vries, Paul S. | |
dc.contributor.author | Demirkan, Ayşe | |
dc.contributor.author | Ding, Jingzhong | |
dc.contributor.author | Eaton, Charles B. | |
dc.contributor.author | Faul, Jessica D. | |
dc.contributor.author | Friedlander, Yechiel | |
dc.contributor.author | Gabriel, Kelley P. | |
dc.contributor.author | Ghanbari, Mohsen | |
dc.contributor.author | Giulianini, Franco | |
dc.contributor.author | Gu, Chi Charles | |
dc.contributor.author | Gu, Dongfeng | |
dc.contributor.author | Harris, Tamara B. | |
dc.contributor.author | He, Jiang | |
dc.contributor.author | Heikkinen, Sami | |
dc.contributor.author | Heng, Chew-Kiat | |
dc.contributor.author | Hunt, Steven C. | |
dc.contributor.author | Ikram, M. Arfan | |
dc.contributor.author | Jonas, Jost B. | |
dc.contributor.author | Koh, Woon-Puay | |
dc.contributor.author | Komulainen, Pirjo | |
dc.contributor.author | Krieger, Jose E. | |
dc.contributor.author | Kritchevsky, Stephen B. | |
dc.contributor.author | Kutalik, Zoltán | |
dc.contributor.author | Kuusisto, Johanna | |
dc.contributor.author | Langefeld, Carl D. | |
dc.contributor.author | Langenberg, Claudia | |
dc.contributor.author | Launer, Lenore J. | |
dc.contributor.author | Leander, Karin | |
dc.contributor.author | Lemaitre, Rozenn N. | |
dc.contributor.author | Lewis, Cora E. | |
dc.contributor.author | Liang, Jingjing | |
dc.contributor.author | Alizadeh, Behrooz Z. | |
dc.contributor.author | Boezen, H. Marike | |
dc.contributor.author | Franke, Lude | |
dc.contributor.author | Navis, Gerjan | |
dc.contributor.author | Rots, Marianne | |
dc.contributor.author | Swertz, Morris | |
dc.contributor.author | Wolffenbuttel, Bruce H. R. | |
dc.contributor.author | Wijmenga, Cisca | |
dc.contributor.author | Liu, Jianjun | |
dc.contributor.author | Mägi, Reedik | |
dc.contributor.author | Manichaikul, Ani | |
dc.contributor.author | Meitinger, Thomas | |
dc.contributor.author | Metspalu, Andres | |
dc.contributor.author | Milaneschi, Yuri | |
dc.contributor.author | Mohlke, Karen L. | |
dc.contributor.author | Mosley, Thomas H. | |
dc.contributor.author | Murray, Alison D. | |
dc.contributor.author | Nalls, Mike A. | |
dc.contributor.author | Nang, Ei-Ei Khaing | |
dc.contributor.author | Nelson, Christopher P. | |
dc.contributor.author | Nona, Sotoodehnia | |
dc.contributor.author | Norris, Jill M. | |
dc.contributor.author | Nwuba, Chiamaka Vivian | |
dc.contributor.author | O’Connell, Jeff | |
dc.contributor.author | Palmer, Nicholette D. | |
dc.contributor.author | Papanicolau, George J. | |
dc.contributor.author | Pazoki, Raha | |
dc.contributor.author | Pedersen, Nancy L. | |
dc.contributor.author | Peters, Annette | |
dc.contributor.author | Peyser, Patricia A. | |
dc.contributor.author | Polasek, Ozren | |
dc.contributor.author | Porteous, David J. | |
dc.contributor.author | Poveda, Alaitz | |
dc.contributor.author | Raitakari, Olli T. | |
dc.contributor.author | Rich, Stephen S. | |
dc.contributor.author | Risch, Neil | |
dc.contributor.author | Robinson, Jennifer G. | |
dc.contributor.author | Rose, Lynda M. | |
dc.contributor.author | Rudan, Igor | |
dc.contributor.author | Schreiner, Pamela J. | |
dc.contributor.author | Scott, Robert A. | |
dc.contributor.author | Sidney, Stephen S. | |
dc.contributor.author | Sims, Mario | |
dc.contributor.author | Smith, Jennifer A. | |
dc.contributor.author | Snieder, Harold | |
dc.contributor.author | Sofer, Tamar | |
dc.contributor.author | Starr, John M. | |
dc.contributor.author | Sternfeld, Barbara | |
dc.contributor.author | Strauch, Konstantin | |
dc.contributor.author | Tang, Hua | |
dc.contributor.author | Taylor, Kent D. | |
dc.contributor.author | Tsai, Michael Y. | |
dc.contributor.author | Tuomilehto, Jaakko | |
dc.contributor.author | Uitterlinden, André G. | |
dc.contributor.author | van der Ende, M. Yldau | |
dc.contributor.author | van Heemst, Diana | |
dc.contributor.author | Voortman, Trudy | |
dc.contributor.author | Waldenberger, Melanie | |
dc.contributor.author | Wennberg, Patrik | |
dc.contributor.author | Wilson, Gregory | |
dc.contributor.author | Xiang, Yong-Bing | |
dc.contributor.author | Yao, Jie | |
dc.contributor.author | Yu, Caizheng | |
dc.contributor.author | Yuan, Jian-Min | |
dc.contributor.author | Zhao, Wei | |
dc.contributor.author | Zonderman, Alan B. | |
dc.contributor.author | Becker, Diane M. | |
dc.contributor.author | Boehnke, Michael | |
dc.contributor.author | Bowden, Donald W. | |
dc.contributor.author | de Faire, Ulf | |
dc.contributor.author | Deary, Ian J. | |
dc.contributor.author | Elliott, Paul | |
dc.contributor.author | Esko, Tõnu | |
dc.contributor.author | Freedman, Barry I. | |
dc.contributor.author | Froguel, Philippe | |
dc.contributor.author | Gasparini, Paolo | |
dc.contributor.author | Gieger, Christian | |
dc.contributor.author | Kato, Norihiro | |
dc.contributor.author | Laakso, Markku | |
dc.contributor.author | Lakka, Timo A. | |
dc.contributor.author | Lehtimäki, Terho | |
dc.contributor.author | Magnusson, Patrik K. E. | |
dc.contributor.author | Oldehinkel, Albertine J. | |
dc.contributor.author | Penninx, Brenda W. J. H. | |
dc.contributor.author | Samani, Nilesh J. | |
dc.contributor.author | Shu, Xiao-Ou | |
dc.contributor.author | van der Harst, Pim | |
dc.contributor.author | Van Vliet-Ostaptchouk, Jana V. | |
dc.contributor.author | Vollenweider, Peter | |
dc.contributor.author | Wagenknecht, Lynne E. | |
dc.contributor.author | Wang, Ya X. | |
dc.contributor.author | Wareham, Nicholas J. | |
dc.contributor.author | Weir, David R. | |
dc.contributor.author | Wu, Tangchun | |
dc.contributor.author | Zheng, Wei | |
dc.contributor.author | Zhu, Xiaofeng | |
dc.contributor.author | Evans, Michele K. | |
dc.contributor.author | Franks, Paul W. | |
dc.contributor.author | Gudnason, Vilmundur | |
dc.contributor.author | Hayward, Caroline | |
dc.contributor.author | Horta, Bernardo L. | |
dc.contributor.author | Kelly, Tanika N. | |
dc.contributor.author | Liu, Yongmei | |
dc.contributor.author | North, Kari E. | |
dc.contributor.author | Pereira, Alexandre C. | |
dc.contributor.author | Ridker, Paul M. | |
dc.contributor.author | Tai, E. Shyong | |
dc.contributor.author | van Dam, Rob M. | |
dc.contributor.author | Fox, Ervin R. | |
dc.contributor.author | Kardia, Sharon L. R. | |
dc.contributor.author | Liu, Ching-Ti | |
dc.contributor.author | Mook-Kanamori, Dennis O. | |
dc.contributor.author | Province, Michael A. | |
dc.contributor.author | Redline, Susan | |
dc.contributor.author | van Duijn, Cornelia M. | |
dc.contributor.author | Rotter, Jerome I. | |
dc.contributor.author | Kooperberg, Charles B. | |
dc.contributor.author | Gauderman, W. James | |
dc.contributor.author | Psaty, Bruce M. | |
dc.contributor.author | Rice, Kenneth | |
dc.contributor.author | Munroe, Patricia B. | |
dc.contributor.author | Fornage, Myriam | |
dc.contributor.author | Cupples, L. Adrienne | |
dc.contributor.author | Rotimi, Charles N. | |
dc.contributor.author | Morrison, Alanna C. | |
dc.contributor.author | Rao, Dabeeru C. | |
dc.contributor.author | Loos, Ruth J. F. | |
dc.contributor.author | Study, Lifelines Cohort | |
dc.date.accessioned | 2019-01-24T09:40:08Z | |
dc.date.available | 2019-01-24T09:40:08Z | |
dc.date.issued | 2019-01-22 | |
dc.identifier | 141787178 | |
dc.identifier | 02ff0db8-eb89-4ccb-80c6-2671aea60d70 | |
dc.identifier | 85060388984 | |
dc.identifier | 30670697 | |
dc.identifier.citation | Kilpeläinen , T O , Bentley , A R , Noordam , R , Sung , Y J , Schwander , K , Winkler , T W , Jakupović , H , Chasman , D I , Manning , A , Ntalla , I , Aschard , H , Brown , M R , de las Fuentes , L , Franceschini , N , Guo , X , Vojinovic , D , Aslibekyan , S , Feitosa , M F , Kho , M , Musani , S K , Richard , M , Wang , H , Wang , Z , Bartz , T M , Bielak , L F , Campbell , A , Dorajoo , R , Fisher , V , Hartwig , F P , Horimoto , A R V R , Li , C , Lohman , K K , Marten , J , Sim , X , Smith , A V , Tajuddin , S M , Alver , M , Amini , M , Boissel , M , Chai , J F , Chen , X , Divers , J , Evangelou , E , Gao , C , Graff , M , Harris , S E , He , M , Hsu , F-C , Jackson , A U , Zhao , J H , Kraja , A T , Kühnel , B , Laguzzi , F , Lyytikäinen , L-P , Nolte , I M , Rauramaa , R , Riaz , M , Robino , A , Rueedi , R , Stringham , H M , Takeuchi , F , van der Most , P J , Varga , T V , Verweij , N , Ware , E B , Wen , W , Li , X , Yanek , L R , Amin , N , Arnett , D K , Boerwinkle , E , Brumat , M , Cade , B , Canouil , M , Chen , Y-D I , Concas , M P , Connell , J , de Mutsert , R , de Silva , H J , de Vries , P S , Demirkan , A , Ding , J , Eaton , C B , Faul , J D , Friedlander , Y , Gabriel , K P , Ghanbari , M , Giulianini , F , Gu , C C , Gu , D , Harris , T B , He , J , Heikkinen , S , Heng , C-K , Hunt , S C , Ikram , M A , Jonas , J B , Koh , W-P , Komulainen , P , Krieger , J E , Kritchevsky , S B , Kutalik , Z , Kuusisto , J , Langefeld , C D , Langenberg , C , Launer , L J , Leander , K , Lemaitre , R N , Lewis , C E , Liang , J , Alizadeh , B Z , Boezen , H M , Franke , L , Navis , G , Rots , M , Swertz , M , Wolffenbuttel , B H R , Wijmenga , C , Liu , J , Mägi , R , Manichaikul , A , Meitinger , T , Metspalu , A , Milaneschi , Y , Mohlke , K L , Mosley , T H , Murray , A D , Nalls , M A , Nang , E-E K , Nelson , C P , Nona , S , Norris , J M , Nwuba , C V , O’Connell , J , Palmer , N D , Papanicolau , G J , Pazoki , R , Pedersen , N L , Peters , A , Peyser , P A , Polasek , O , Porteous , D J , Poveda , A , Raitakari , O T , Rich , S S , Risch , N , Robinson , J G , Rose , L M , Rudan , I , Schreiner , P J , Scott , R A , Sidney , S S , Sims , M , Smith , J A , Snieder , H , Sofer , T , Starr , J M , Sternfeld , B , Strauch , K , Tang , H , Taylor , K D , Tsai , M Y , Tuomilehto , J , Uitterlinden , A G , van der Ende , M Y , van Heemst , D , Voortman , T , Waldenberger , M , Wennberg , P , Wilson , G , Xiang , Y-B , Yao , J , Yu , C , Yuan , J-M , Zhao , W , Zonderman , A B , Becker , D M , Boehnke , M , Bowden , D W , de Faire , U , Deary , I J , Elliott , P , Esko , T , Freedman , B I , Froguel , P , Gasparini , P , Gieger , C , Kato , N , Laakso , M , Lakka , T A , Lehtimäki , T , Magnusson , P K E , Oldehinkel , A J , Penninx , B W J H , Samani , N J , Shu , X-O , van der Harst , P , Van Vliet-Ostaptchouk , J V , Vollenweider , P , Wagenknecht , L E , Wang , Y X , Wareham , N J , Weir , D R , Wu , T , Zheng , W , Zhu , X , Evans , M K , Franks , P W , Gudnason , V , Hayward , C , Horta , B L , Kelly , T N , Liu , Y , North , K E , Pereira , A C , Ridker , P M , Tai , E S , van Dam , R M , Fox , E R , Kardia , S L R , Liu , C-T , Mook-Kanamori , D O , Province , M A , Redline , S , van Duijn , C M , Rotter , J I , Kooperberg , C B , Gauderman , W J , Psaty , B M , Rice , K , Munroe , P B , Fornage , M , Cupples , L A , Rotimi , C N , Morrison , A C , Rao , D C , Loos , R J F & Study , L C 2019 , ' Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity ' , Nature Communications , vol. 10 , no. 1 , 376 . https://doi.org/10.1038/s41467-018-08008-w | en |
dc.identifier.issn | 2041-1723 | |
dc.identifier.other | RIS: urn:066700F4141B8F8DD77249F7E6128D00 | |
dc.identifier.other | RIS: Kilpeläinen2019 | |
dc.identifier.other | Mendeley: 138c33ca-b490-3d29-859a-a53eea959ab9 | |
dc.identifier.other | ORCID: /0000-0003-4915-4847/work/76976593 | |
dc.identifier.uri | http://hdl.handle.net/2164/11826 | |
dc.description | The present work was largely supported by a grant from the US National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health (R01HL118305). The full list of acknowledgments appears in the Supplementary Notes 3 and 4. | en |
dc.format.extent | 11 | |
dc.format.extent | 1792872 | |
dc.language.iso | eng | |
dc.relation.ispartof | Nature Communications | en |
dc.subject | Adolescent | en |
dc.subject | Adult | en |
dc.subject | African Continental Ancestry Group/genetics | en |
dc.subject | Aged | en |
dc.subject | Aged, 80 and over | en |
dc.subject | Asian Continental Ancestry Group/genetics | en |
dc.subject | Brazil | en |
dc.subject | Calcium-Binding Proteins/genetics | en |
dc.subject | Cholesterol, HDL/blood | en |
dc.subject | Cholesterol, LDL/blood | en |
dc.subject | Cholesterol/blood | en |
dc.subject | European Continental Ancestry Group/genetics | en |
dc.subject | Exercise | en |
dc.subject | Female | en |
dc.subject | Genetic Loci/genetics | en |
dc.subject | Genome-Wide Association Study | en |
dc.subject | Genotype | en |
dc.subject | Hispanic Americans/genetics | en |
dc.subject | Humans | en |
dc.subject | LIM-Homeodomain Proteins/genetics | en |
dc.subject | Lipid Metabolism/genetics | en |
dc.subject | Lipids/blood | en |
dc.subject | Male | en |
dc.subject | Membrane Proteins/genetics | en |
dc.subject | Microtubule-Associated Proteins/genetics | en |
dc.subject | Middle Aged | en |
dc.subject | Muscle Proteins/genetics | en |
dc.subject | Nerve Tissue Proteins/genetics | en |
dc.subject | Transcription Factors/genetics | en |
dc.subject | Triglycerides/blood | en |
dc.subject | Young Adult | en |
dc.subject | R Medicine (General) | en |
dc.subject | General Physics and Astronomy | en |
dc.subject | General Chemistry | en |
dc.subject | General Biochemistry,Genetics and Molecular Biology | en |
dc.subject | Supplementary Data | en |
dc.subject | Supplementary data available | en |
dc.subject.lcc | R1 | en |
dc.title | Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity | en |
dc.type | Journal article | en |
dc.contributor.institution | University of Aberdeen.Applied Medicine | en |
dc.contributor.institution | University of Aberdeen.Grampian Data Safe Haven (DaSH) | en |
dc.contributor.institution | University of Aberdeen.Institute of Medical Sciences | en |
dc.contributor.institution | University of Aberdeen.Aberdeen Biomedical Imaging Centre | en |
dc.description.status | Peer reviewed | en |
dc.identifier.doi | 10.1038/s41467-018-08008-w | |
dc.identifier.url | http://www.scopus.com/inward/record.url?scp=85060388984&partnerID=8YFLogxK | en |
dc.identifier.url | http://www.mendeley.com/research/multiancestry-study-blood-lipid-levels-identifies-four-loci-interacting-physical-activity | en |