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Increasing levels of the endocannabinoid 2-AG is neuroprotective in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease

dc.contributor.authorMounsey, Ross B
dc.contributor.authorMustafa, Sarah
dc.contributor.authorRobinson, Lianne
dc.contributor.authorRoss, Ruth A.
dc.contributor.authorRiedel, Gernot
dc.contributor.authorPertwee, Roger G.
dc.contributor.authorTeismann, Peter
dc.date.accessioned2015-08-06T14:33:06Z
dc.date.available2015-08-06T14:33:06Z
dc.date.issued2015-11
dc.identifier54308303
dc.identifierb32ff204-0cb4-4926-97d2-65ac5336bd97
dc.identifier000365151800004
dc.identifier84939154942
dc.identifier000365151800004
dc.identifier.citationMounsey , R B , Mustafa , S , Robinson , L , Ross , R A , Riedel , G , Pertwee , R G & Teismann , P 2015 , ' Increasing levels of the endocannabinoid 2-AG is neuroprotective in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease ' , Experimental Neurology , vol. 273 , pp. 36-44 . https://doi.org/10.1016/j.expneurol.2015.07.024en
dc.identifier.issn0014-4886
dc.identifier.urihttp://hdl.handle.net/2164/4787
dc.descriptionDate of Acceptance: 28/07/2015 The authors are grateful to the staff of the Medical Research Facility for their help with the animal care. This work was supported by the NHS Endowment fund 09/03 and the Wellcome Trust (WT080782MF). We thank Merck & Co. Inc., Rathway NJ, USA for the supply of DFU.en
dc.format.extent9
dc.format.extent1831427
dc.language.isoeng
dc.relation.ispartofExperimental Neurologyen
dc.subjectEndocannabinoidsen
dc.subjectParkinson's diseaseen
dc.subjectMPTPen
dc.subjectNeuroprotectionen
dc.subjectCB1 cannabinoid receptorsen
dc.subjecttoxicity in-vivoen
dc.subjectmonoacylglycerol lipaseen
dc.subjectHuntingtons-Diseaseen
dc.subjectcerebrospinal-fluiden
dc.subjectAlzheimers-Diseaseen
dc.subjectinduced neurotoxicityen
dc.subjectup-regulationen
dc.subjectfactor-alphaen
dc.subjectbrainen
dc.subjectRC0321 Neuroscience. Biological psychiatry. Neuropsychiatryen
dc.subjectWellcome Trusten
dc.subject.lccRC0321en
dc.titleIncreasing levels of the endocannabinoid 2-AG is neuroprotective in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's diseaseen
dc.typeJournal articleen
dc.contributor.institutionUniversity of Aberdeen.Medical Sciencesen
dc.description.statusPeer revieweden
dc.identifier.doi10.1016/j.expneurol.2015.07.024
dc.identifier.vol273en


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