dc.contributor.author | Cuthbertson, Brian | en |
dc.contributor.author | Card, Gemma | |
dc.contributor.author | Croal, Bernard L. | |
dc.contributor.author | McNeilly, Jane | |
dc.contributor.author | Hillis, Graham | |
dc.date.accessioned | 2008-12-03T10:07:00Z | |
dc.date.available | 2008-12-03T10:07:00Z | |
dc.date.issued | 2007-09 | |
dc.identifier.citation | Cuthbertson, B.H., Card, G., Coral, B.L., McNeilly, J., and Hillis, G. (2007). The utility of B-type natriuretic peptide in predicting postoperative cardiac events and mortality in patients undergoing major emergency non-cardiac surgery. Anaesthesia, 62(9), pp.875-881. | en |
dc.identifier.issn | 0003-2409 | |
dc.identifier.other | PURE: 349308 | en |
dc.identifier.uri | http://hdl.handle.net/2164/263 | |
dc.description.abstract | B-type natriuretic peptide (BNP) levels predict cardiovascular risk in several settings. We hypothesized that they would identify individuals at increased risk of complications and mortality following major emergency non-cardiac surgery.Forty patients were studied with a primary end-point of a new post-operative cardiac event, and/or development of significant ECG changes, and/or cardiac death. The main secondary outcome was all cause mortality at 6 months. Preoperative BNP levels were higher in 11 patients who suffered a new postoperative cardiac event (p=0.001) and predicted this outcome with an area under the receiver operating characteristic curve of 0.85 (CI=0.72-0.98,p=0.001). A pre-operative BNP value >170pg.ml-1 has a sensitivity of 82% and a specificity of 79% for the primary end-point. In this small study, pre-operative BNP levels identify patients undergoing major emergency non-cardiac surgery who are at increased risk of early post-operative cardiac events. Larger studies are required to confirm these data. | en |
dc.format.extent | 137049 bytes | |
dc.format.extent | 6 p. | en |
dc.format.mimetype | application/pdf | |
dc.language.iso | en | en |
dc.publisher | Blackwell | en |
dc.source.uri | The definitive version is available at www3.interscience.wiley.com | en |
dc.subject | B-type natriuretic peptide | en |
dc.subject | non-cardiac surgery | en |
dc.subject | emergency surgery | en |
dc.subject | risk stratification | en |
dc.subject.lcc | RD Surgery | en |
dc.title | The utility of B-type natriuretic peptide in predicting postoperative cardiac events and mortality in patients undergoing major emergency non-cardiac surgery | en |
dc.type | Journal Article | en |
dc.type | Text | en |
dc.contributor.institution | University of Aberdeen, School of Medicine & Dentistry, Division of Applied Health Sciences | en |
dc.description.status | Peer reviewed | en |
dc.description.version | Preprint | en |
dc.identifier.doi | http://dx.doi.org/10.1111/j.1365-2044.2007.05146.x | |